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Now showing items 21-28 of 28
The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study
(2019-02)
Background:
The discovery that voltage-gated calcium channel genes such as CACNA1C are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic potential of L-type calcium channel (LTCC) ...
Short-term memory advantage for brief durations in human APOE ε4 carriers
(2020-06)
The Apolipoprotein-E (APOE) ε4 gene allele, the highest known genetic risk factor for Alzheimer’s disease, has paradoxically been well preserved in the human population. One possible explanation offered by evolutionary ...
A between-task consequence of temporal expectations
(2021-11)
In everyday life, we often anticipate the timing of one upcoming task or event while actively engaging in another. Here, we investigated temporal expectations within such a multi-task scenario. In a visual working-memory ...
The effect of sertraline on emotional processing: secondary analyses of the PANDA randomised controlled trial
(2021-01)
Background. According to the cognitive neuropsychological model, antidepressants reduce
symptoms of depression and anxiety by increasing positive relative to negative information processing. Most studies of whether ...
The relationship between short- and long-term memory is preserved across the age range
(2022-06)
The aim of the current study was to examine cross-sectionally the changes in the relationship
between short- and long-term memory with age. In two experiments, participants across the
age-range were tested on contextual-spatial ...
Patient attitudes towards remote memory clinic assessment
(2021-12)
Background: Due to demand on UK memory clinic services, most patients have limited consultant interaction before diagnosis/discharge. Technology offers an opportunity for remote assessment, from telephone/video-based ...
Effects of ulotaront on brain circuits of reward, working memory, and emotion processing in healthy volunteers with high or low schizotypy
(2023-08)
Ulotaront, a trace amine-associated receptor 1 (TAAR1) and serotonin 5-HT1A receptor agonist without antagonist activity at dopamine D2 or the serotonin 5-HT2A receptors, has demonstrated efficacy in the treatment of ...
Impaired subjective organisation of memory in psychogenic amnesia
(2023-08)
Objectives: Psychogenic or dissociative amnesia is a rare condition which involves primarily impairment in episodic
autobiographical memory. Why such impairment occurs in such patients has always perplexed researchers and ...