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How women with and without eating disorders perceive their own and others’ bodies: a case-control study
(University of Bristol, 2020-03)
Background: Body dissatisfaction is a key part of the
psychopathology of eating disorders, but there is a lack of consensus
as to whether the dissatisfaction arises from misperception of body
size, and if such misperception ...
Does repeatedly viewing overweight versus underweight images change perception of and satisfaction with own body size?
(2020-04)
Body dissatisfaction is associated with subsequent eating disorders and weight gain. One-off exposure to bodies of different sizes changes perception of others' bodies, and perception of and satisfaction with own body size. ...
Cognitive neuropsychological theory of antidepressant action: a modern-day approach to depression and its treatment
(2020-01)
Depression is a leading cause of disability worldwide and improving its treatment is a core research priority for future programmes. A change in the view of psychological and biological processes, from seeing them as ...
Effect of the NMDA receptor partial agonist, d-cycloserine, on emotional processing and autobiographical memory
(2020-04)
Background: Studies suggest that d-cycloserine (DCS) may have antidepressant potential through its interaction with the glycine site of the N-Methyl-D-aspartate receptor (NMDAR); however clinical evidence of DCS’s efficacy ...
How representative are neuroimaging samples? Large-scale evidence for trait anxiety differences between MRI and behaviour-only research participants.
(2020-04)
Over the past three decades, MRI has become a key tool to study how cognitive processes are implemented in the human brain. However, the question of whether participants recruited into MRI studies differ from participants ...
Cognition in Mood Disorders
(2020-01)
Mood disorders are common, complex, and one of the main causes of morbidity worldwide (1).
There has been an increasing recognition that cognitive dysfunction is a central aspect of most
mood disorders, as well as being ...
A single administration of ‘microbial’ D-alanine to healthy volunteers augments reaction to negative emotions: a comparison with D-serine
(2020-03)
Background Activation of the glutamate N-methyl-D-Aspartate receptor (NMDAR) with its co-agonist D-serine has been shown to improve subjective mood in healthy volunteers. D-alanine is another potent NMDAR co-agonist which ...
Neurocognitive processes in d-cycloserine augmented single-session exposure therapy for anxiety: A randomized placebo-controlled trial
(2020-06)
Drugs targeting N-methyl-d-aspartate (NMDA) receptors and the ability to learn new associations have been proposed as adjunct treatments to boost the success of exposure therapy for anxiety disorders. However, the effects ...
Neural effects of a single dose of fluoxetine on resting-state functional connectivity in adolescent depression
(2020-11)
Fluoxetine is commonly prescribed in adolescent depression, but the neural mechanisms underlying its action remain poorly understood. Here, we used resting-state functional magnetic resonance imaging to investigate the ...
Precision biomarkers for mood disorders based on brain imaging
(2020-10)
Mood disorders are a global public health problem because of their high prevalence, chronicity, and recurrence throughout the lifespan as well as increased risk of mortality.123 They also impose a heavy economic burden on ...