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Ketamine treatment for depression: qualitative study exploring patient views
(2021-01)
Ketamine is a new and promising treatment for depression but comes with challenges to implement because of its potential for abuse.
Aims
We sought the views of patients to inform policy and practical decisions about ...
Hierarchical modelling of functional brain networks in population and individuals from big fMRI data
(2021-02)
A major goal of large-scale brain imaging datasets is to provide resources for investigating heterogeneous
populations. Characterisation of functional brain networks for individual subjects from these datasets will have
an ...
Effect of glucose and sucrose on cognition in healthy humans: a systematic review and meta-analysis of interventional studies
(2021-02)
Evidence suggests that plasma glucose levels may influence cognitive performance, but this has not been systematically reviewed and quantified. Objective: The aim of this review was to investigate the potential effects of ...
Mapping brain structural differences and neuroreceptor correlates in Parkinson's disease visual hallucinations: a mega-analysis
(2021-02)
Parkinson’s psychosis (PDP) describes a spectrum of symptoms that may arise in Parkinson’s disease (PD)
including visual hallucinations (VH). Imaging studies investigating the neural correlates of PDP have been
inconsistent ...
The neurology and neuropsychiatry of COVID-19: a systematic review and meta-analysis of the early literature reveals frequent CNS manifestations and key emerging narratives
(2021-02)
There is accumulating evidence of the neurological and neuropsychiatric features of infection with SARS-CoV-2.
In this systematic review and meta-analysis, we aimed to describe the characteristics of the early literature ...
Individual variation in brain microstructural-cognition relationships in aging
(2021-02)
While all individuals are susceptible to age-related cognitive decline, significant inter- and
intra-individual variability exists. However, the sources of this variation remain poorly understood. Here,
we examined the ...
Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)
Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with
polypharmacy, but there is little evidence to inform which drug (or dose) should be
withdrawn. This study used data from the ...
An Intuitive Risk Communication Tool to Enhance Patient–Provider Partnership in Diabetes Consultation
(2021-02)
Introduction: This technology report introduces an innovative risk communication tool developed to support providers in
communicating diabetes-related risks more intuitively to people with type 2 diabetes mellitus ...
Development and Validation of a Novel Dementia Risk Score in the UK Biobank Cohort
(2021-03)
INTRODUCTION: Current prognostic models of dementia have had limited success in consistently identifying at-risk individuals. We aimed to develop and validate a novel dementia risk score (DRS) using the UK Biobank cohort. ...
Output planning at the input stage in visual working memory
(2021-03)
Working memory serves as the buffer between past sensations and future behavior, making it vital to understand not only how we encode and retain sensory information in memory but also how we plan for its upcoming use. We ...