Browsing Genetics by Author "Harrison, Paul J"
Now showing items 1-4 of 4
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Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders
Harrison, Paul J (2018-08)Sleep EEG spindles have been implicated in attention, sensory processing, synaptic plasticity and memory consolidation. In humans, deficits in sleep spindles have been reported in a wide range of neurological and psychiatric ... -
Accurate expression quantification from nanopore direct RNA sequencing with NanoCount
Harrison, Paul J (2021-11)Accurately quantifying gene and isoform expression changes is essential to understanding cell functions, differentiation and disease. Sequencing full-length native RNAs using long-read direct RNA sequencing (DRS) has the ... -
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression
Tunbridge, Elizabeth; Harrison, Paul J (2018)Risk-taking behaviour is an important component of several psychiatric disorders, including attention-deficit hyperactivity disorder, schizophrenia and bipolar disorder. Previously, two genetic loci have been associated ... -
Which Dopamine Polymorphisms are Functional? Systematic Review and Meta-Analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1 and VMAT2
Tunbridge, Elizabeth; Cipriani, Andrea; Harrison, Paul J (2019-05)BACKGROUND: Many polymorphisms in dopamine genes are reported to affect cognitive, imaging or clinical phenotypes. It is often inferred or assumed that such associations are causal, mediated by a direct effect of the ...