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Dopaminergic modulation of regional cerebral blood flow: An arterial spin labelling study of genetic and pharmacological manipulation of COMT activity
(2021-07)
Dopamine has direct and complex vasoactive effects on cerebral circulation. Catechol-O-methyltransferase (COMT) regulates cortical dopamine, and its activity can be influenced both genetically and pharmacologically. COMT ...
Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
(2021-04)
Alternative splicing (AS) is a key mechanism underlying cellular differentiation and a driver of
complexity in mammalian neuronal tissues. However, understanding of which isoforms are
differentially used or expressed and ...