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Now showing items 1-10 of 12
A year in statistics—the view from the trenches
(2020-01)
Editorial: Last year we launched the EBM Methods Verdicts as part of an attempt to keep on top of developments in statistics that will impact on the way we do research.1 2 We focused on statistical methods and in particular ...
Development of A Guideline for Reporting Mediation Analyses (AGReMA)
(2020-02)
There are a growing number of studies using mediation analysis to understand the mechanisms of health interventions and exposures. Recent work has shown that the reporting of these studies is heterogenous and incomplete. ...
The Kilim plot: A tool for visualizing network meta‐analysis results for multiple outcomes
(2020-06)
Network meta‐analysis (NMA) can be used to compare multiple competing treatments for the same disease. In practice, usually a range of outcomes is of interest. As the number of outcomes increases, summarizing results from ...
Ethical challenges in Research, Industry and People Partnerships in mental health
(2020-08)
Advancements in mental health research, social changes and policy developments have led to the emergence
of new forms of research partnerships, which bring together research institutions, public companies and lay
people ...
Pharmaceutical industry, academia and people with experience of mental illness as partners in research: a need for ethical guidance [version 1; peer review: 1 not approved]
(2020-08)
Background: Several social and policy developments have led to research partnerships in mental health research, which depart from traditional research models. One form of such partnerships is among research institutions, ...
Ethical Issues in Consent for the Re-use of Data in Health Data Platforms
(2020-12)
Data platforms represent a new paradigm for carrying out health research. In the platform model, datasets are pooled for remote access and analysis, so novel insights for developing better stratified and / or personalised ...
Ethical implications of poor comparative effectiveness evidence: obligations in industry-research partnerships
(2020-03)
Which treatment is best for me? This question is at the centre of the clinical consultation. And yet, too often, the question is not answerable with available evidence on drugs and devices. The two Lancet Series papers on ...
Investigating assumptions of vulnerability: A case study of the exclusion of psychiatric inpatients as participants in genetic research in low‐ and middle‐income contexts
(2020-01)
Psychiatric genetic research investigates the genetic basis of psychiatric disorders with the aim of more effectively understanding, treating, or, ultimately, preventing such disorders. Given the challenges of recruiting ...
Informing National Health Service patients about participation in clinical research: A comparison of opt-in and opt-out approaches across the United Kingdom
(2020-11)
Objective:
Recruitment to clinical research in the National Health Service remains challenging. One barrier is accessing patients to discuss research participation. Two general approaches are used in the United Kingdom ...
When Deploying Predictive Algorithms, Are Summary Performance Measures Sufficient?
(2020-01)
The last decade’s growth in artificial intelligence, machine learning, and statistical methods for high-dimensional data has driven a zeitgeist of prediction (or forecasting) in medicine and psychiatry. Algorithms for ...