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Mixed effects approach to the analysis of the stepped wedge cluster randomised trial—Investigating the confounding effect of time through simulation
(2018-12)
A stepped wedge cluster randomised trial (SWCRT) is a multicentred study which allows an intervention to be rolled out at sites in a random order. Once the intervention is initiated at a site, all participants within that ...
Ethical challenges in Research, Industry and People Partnerships in mental health
(2020-08)
Advancements in mental health research, social changes and policy developments have led to the emergence
of new forms of research partnerships, which bring together research institutions, public companies and lay
people ...
Network meta-analysis of antidepressants – Authors' reply
(2018-09-22)
Comments on issues raised with Cipriani et al, 'Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis' ...
Consent to discuss participation in research: a pilot study
(2019-09)
Background. Equitable access to research studies needs to be increased for all patients. There is debate about which is the best approach to use to discuss participation in research in real-world clinical settings.
Objective. ...
Informing National Health Service patients about participation in clinical research: A comparison of opt-in and opt-out approaches across the United Kingdom
(2020-11)
Objective:
Recruitment to clinical research in the National Health Service remains challenging. One barrier is accessing patients to discuss research participation. Two general approaches are used in the United Kingdom ...
A web-based clinical decision tool to support treatment decision-making in psychiatry: a pilot focus group study with clinicians, patients and carers
(2017)
Background
Treatment decision tools have been developed in many fields of medicine, including psychiatry, however benefits for patients have not been sustained once the support is withdrawn. We have developed a web-based ...
A narrative review of the success of intramuscular gluteal injections and its impact in psychiatry
(2018-07)
There are 12 billion injections given worldwide every year. For many injections, the intramuscular route is favoured over the subcutaneous route due to the increased vascularity of muscle tissue and the corresponding ...
When Deploying Predictive Algorithms, Are Summary Performance Measures Sufficient?
(2020-01)
The last decade’s growth in artificial intelligence, machine learning, and statistical methods for high-dimensional data has driven a zeitgeist of prediction (or forecasting) in medicine and psychiatry. Algorithms for ...