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Real-world effect of antidepressants for depressive disorder in primary care: protocol of a population-based cohort study
(2020-06)
Introduction Clinical guidelines recommend antidepressants as the first line of treatment for adults with moderate-to-severe depression. Randomised trials provide the best evidence on the comparative effectiveness of ...
Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis
(2020-03)
Background
The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies ...