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No benefit from flexible titration above minimum licensed dose in prescribing antidepressants for major depression: systematic review
(2019-12)
Background
In fixed‐dose antidepressant trials, the lower range of the licensed dose achieves the optimal balance between efficacy and tolerability. Whether flexible upward titration while side‐effects permit provides ...
A single dose of fluoxetine reduces neural limbic responses to anger in depressed adolescents
(2019-01-21)
Depression in adolescence is frequently characterised by symptoms of irritability. Fluoxetine is the antidepressant with
the most favourable benefit:risk ratio profile to treat adolescent depression, but the neural ...