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Development and Validation of a Novel Dementia Risk Score in the UK Biobank Cohort
(2021-03)
INTRODUCTION: Current prognostic models of dementia have had limited success in consistently identifying at-risk individuals. We aimed to develop and validate a novel dementia risk score (DRS) using the UK Biobank cohort. ...
Study Protocol: The Heart and Brain Study
(2021-03)
Background: It is well-established that what is good for the heart is good for the brain. Vascular factors such as hypertension, diabetes, and high cholesterol, and genetic factors such as the apolipoprotein E4 allele ...
Effect of trazodone on cognitive decline in people with dementia: Cohort study using UK routinely collected data
(2021-09)
Evidence in mouse models has found that the antidepressant trazodone may be protective against neurodegeneration. We therefore aimed to compare cognitive decline of people with dementia taking trazodone with those taking ...
Patient attitudes towards remote memory clinic assessment
(2021-12)
Background: Due to demand on UK memory clinic services, most patients have limited consultant interaction before diagnosis/discharge. Technology offers an opportunity for remote assessment, from telephone/video-based ...