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Multi-scale neural signatures of major depressive, anxiety, and stress-related disorders
(2021-07)
The extent of shared and distinct neural mechanisms underlying major depressive disorder (MDD), anxiety and stress-related disorders is still unclear. We compared the neural signatures of these disorders in 5,405 UK Biobank ...
The knowns and unknowns of SSRI treatment in young people with depression and anxiety: efficacy, predictors, and mechanisms of action
(2021-08)
The use of SSRIs for the treatment of depression and anxiety in young people is increasing. However, the effects of SSRIs in adolescence, a time when there are substantial changes in neural, cognitive, and social functioning, ...
Severity of Post-Stroke Cognitive Impairment Moderates the Relationship Between Cognitive Change and Emotional Distress in the Months Following Stroke
(2021-09)
Depression and anxiety are common psychological consequences of stroke. Here, we
investigated the relationships between cognitive change following stroke, awareness of
cognitive impairments, and mood to further understanding ...
Implementing a stepped-care psychological pathway for cardiac patients with comorbid anxiety and depression in the UK: a service development project
(2021-03)
Background/aims
This was a pilot study that was part of a Department of Health and Social Care initiative to improve access to cognitive behavioural therapies for patients with long-term health conditions. The service ...