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Value of monitoring negative emotional bias in primary care in England for personalised antidepressant treatment: a modelling study
(2019-11)
Depressed patients often focus on negative life events. Effective antidepressant therapy reverses this negative emotional bias (NEB) within 1 week. Clinical therapeutic effect usually requires 4–6 weeks. The value of ...
Predicting Treatment Response to Antidepressant Medication Using Early Changes in Emotional Processing.
(2019-01)
Antidepressants must be taken for weeks before response can be assessed with many patients not responding to the first medication prescribed. This often results in long delays before effective treatment is started. ...
No antidepressant-like acute effects of bright light on emotional information processing in healthy volunteers
(2021-11)
Rationale: Bright light treatment (BLT) is an efficacious antidepressant intervention, but its mechanism of action is not well understood. Antidepressant drugs acutely affect how emotional information is processed, pushing ...
The effect of sertraline on emotional processing: secondary analyses of the PANDA randomised controlled trial
(2021-01)
Background. According to the cognitive neuropsychological model, antidepressants reduce
symptoms of depression and anxiety by increasing positive relative to negative information processing. Most studies of whether ...
Subchronic treatment with St John’s wort produces a positive shift in emotional processing in healthy volunteers
(2018-11-28)
The neurocognitive model of antidepressant treatment in depression states that antidepressants work by producing relatively immediate positive shifts in emotional processing, which translate into clinical improvement with ...
Catechol-O-methyltransferase activity does not influence emotional processing in men
(2022-04)
Background: Catechol-O-methyltransferase (COMT) regulates cortical dopaminergic transmission and prefrontal-dependent cognitive function. However, its role in other cognitive processes, including emotional processing, is ...