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Now showing items 1-10 of 10
Disrupting the power balance between doctors and patients in the digital era
(2021-01)
The primary way of identifying symptoms of impending disease, and when it is time to seek care, relies heavily on a patient's own perception of how they feel. This reliance on a disease reaching a threshold at which ...
Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
(2021-01)
Background. Neurological and psychiatric sequelae of COVID-19 have been reported, but
there are limited data on incidence rates and relative risks.
Methods. Using retrospective cohort studies and time-to-event analysis, ...
Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine
(2021-04)
Objectives To estimate the absolute risk of cerebral venous thrombosis (CVT) and portal vein thrombosis (PVT) in the two weeks following a diagnosis of COVID-19, and to assess the relative risks (RR) compared to influenza ...
A retrospective examination of care pathways in individuals with treatment-resistant depression
(2021-05)
Individuals with treatment-resistant depression (TRD) experience a high burden of illness. Current guidelines recommend a stepped care approach for treating depression, but the extent to which best-practice care pathways ...
Incidence and outcomes of eating disorders during the COVID-19 pandemic
(2021-07)
There are concerns that eating disorders have become commoner during the coronavirus disease 2019 (COVID-19) pandemic. Using the electronic health records of 5.2 million people aged under 30, mostly in the USA, we show ...
Effect of lithium on circadian rhythm in bipolar disorder: A systematic review and meta-analysis
(2021-03)
Circadian rhythm disruption is commonly reported in patients with bipolar disorder. Lithium has been suggested to have effects on the circadian clock, the biological basis of the circadian rhythm. The objective of the ...
The costs of bipolar disorder in the United Kingdom
(2021-09)
Objectives: To estimate the individual cost and population-level economic burden of Bipolar Disorder (BD), and explore the impact of clinical and sociodemographic factors on costs in the United Kingdom.
Methods: Annual ...
Study protocol for a randomised placebo-controlled trial of pramipexole in addition to mood stabilisers for patients with treatment resistant bipolar depression (the PAX-BD study)
(2021-07)
Treatment Resistant Bipolar Depression (TRBD) is a major contributor to the burden of disease associated with Bipolar Disorder (BD). Treatment options for people experiencing bipolar depression are limited to three ...
Association of Schizophrenia Spectrum Disorders and Violence Perpetration in Adults and Adolescents From 15 Countries A Systematic Review and Meta-analysis
(2021-12)
Violence perpetration outcomes in individuals with schizophrenia spectrum disorders contribute to morbidity and mortality at a population level, disrupt care, and lead to stigma.
Objective : To conduct a systematic ...
Use of online cultural content for mental health and well-being during COVID-19 restrictions: cross-sectional survey
(2021-11)
Aims and method To gain a deeper understanding of the use of online culture and
its potential benefits to mental health and well-being, sociodemographic
characteristics and self-reported data on usage, perceived mental ...