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Smartphones and Wearables as a Method for Understanding Symptom Mechanisms
(2020-01)
While psychological treatments have been shown to be effective in treating psychiatric disorders, the mechanism of their therapeutic effect is less well understood. An improved mechanistic understanding of psychiatric ...
Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces
(2020-03)
Contemporary theories propose that dysregulation of emotional perception is involved in the aetiology of psychosis. 298 healthy adolescents were assessed at age 14- and 19-years using fMRI while performing a facial emotion ...
Unraveling Mechanisms of Patient-Specific NRXN1 Mutations in Neuropsychiatric Diseases Using Human Induced Pluripotent Stem Cells
(2020-03)
Rare heterozygous deletions in the neurexin 1 (NRXN1) gene robustly increase an individual's risk of developing neurological and psychiatric disorders. However, the molecular bases by which different mutations result in ...
Sleep disturbance and psychiatric disorders
(2020-07)
Signs of mental ill health that cut across psychiatric diagnostic categories at high rates are typically viewed as non-specific occurrences, downgraded in importance and disregarded. However, problems not associated with ...
7 Virtual reality (VR) for the treatment of mental health disorders
(2020-07)
Mental health disorders are very common, but far too few people receive the best treatments. Much greater access to the best psychological treatments may be achieved using automated delivery in virtual reality (VR). With ...
Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA
(2020)
Background
Adverse mental health consequences of COVID-19, including anxiety and depression, have been widely predicted but not yet accurately measured. There are a range of physical health risk factors for COVID-19, but ...
A Structural Brain Network of Genetic Vulnerability to Psychiatric Illness
(2020-05)
Psychiatry is undergoing a paradigm shift from the acceptance of distinct diagnoses to a representation of psychiatric illness that crosses diagnostic boundaries. How this transition is supported by a shared neurobiology ...
Environmental changes to reduce self-harm on an adolescent inpatient psychiatric ward: an interrupted time series analysis
(2020-07)
Existing interventions to reduce self-harm in adolescents admitted to psychiatric wards are usually focused on individual psychological treatments. However, the immediate ward environment in which treatment takes place is ...
Covid-19 and mental health: a transformational opportunity to apply an evidence-based approach to clinical practice and research
(2020-04)
The Oxford Precision Psychiatry Lab (https://oxfordhealthbrc.nihr.ac.uk/our-work/oxppl/, @OxfordPPL) collected from senior clinicians in the local Mental Health Trust a list of specific and focused questions about mental ...
Fear of illness recurrence and mental healthanxiety in people recovering from psychosis andcommon mental health problems
(2020-06)
Objectives: It is well known that mental health problems can recur even after effective treatment, leading to an understandable fear of illness recurrence (FIR) and mental health anxiety (MHA). These may themselves contribute ...