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Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)
Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with
polypharmacy, but there is little evidence to inform which drug (or dose) should be
withdrawn. This study used data from the ...
Risk Factors for Mobility Decline in Community-Dwelling Older Adults: A Systematic Literature Review
(2021-08)
Mobility is essential to maintaining independence for older adults. This systematic review aimed to summarize evidence about
self-reported risk factors for self-reported mobility decline; and to provide an overview of ...
Altered network stability in progressive supranuclear palsy
(2021-07)
The clinical syndromes of Progressive Supranuclear Palsy (PSP) may be mediated by abnormal temporal dynamics of brain networks, due to the impact of atrophy, synapse loss and neurotransmitter deficits. We tested the ...
Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate
(2021-11)
Older adults exposed to enriched environments (EE) maintain relatively higher levels of cognitive function, even in the face of compromised markers of brain health. Response speed (RS) is often used as a simple proxy to ...