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Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal
(2019-06)
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and ...
Exercise- and strategy-based physiotherapy-delivered intervention for preventing repeat falls in people with Parkinson's: the PDSAFE RCT.
(2019-07)
BACKGROUND: People with Parkinson's disease are twice as likely to experience a fall as a healthy older person, often leading to debilitating effects on confidence, activity levels and quality of life.
OBJECTIVE: To ...
Does cranberry extract reduce antibiotic use for symptoms of acute uncomplicated urinary tract infections (CUTI)? Protocol for a feasibility study
(2019-12)
Consultations in primary care for symptoms of urinary tract infections (UTIs) are common and patients are frequently treated with antibiotics. Given increasing antimicrobial resistance, there has been interest in non-antibiotic ...
No benefit from flexible titration above minimum licensed dose in prescribing antidepressants for major depression: systematic review
(2019-12)
Background
In fixed‐dose antidepressant trials, the lower range of the licensed dose achieves the optimal balance between efficacy and tolerability. Whether flexible upward titration while side‐effects permit provides ...
Variation in spend on young mental health across Clinical Commissioning Groups in England: a cross-sectional observational study
(2019-08)
Objectives To investigate whether the rate of spend
on child and adolescent mental health is influenced
by demand for other competing services in local
commissioning decisions.
Design Analysis of spend data by Clinical ...
REBT and Psychosis
(2019-02)
Until comparatively recently, the idea of using REBT or any kind of cognitive psychotherapy for schizophrenia sounded like an oxymoron. The prevailing view in psychiatry and widely in the mental health field, was—and ...
Understanding, treating, and renaming grandiosedelusions: A qualitative study
(2019-11)
Background.Grandiose delusions are arguably the most neglected psychotic experience in research.
Objectives.We aimed to discover from patients: whether grandiose delusions have harmful consequences; the psychological ...
Experiences of Reframing during Self-Directed Weight Loss and Weight Loss Maintenance: Systematic Review of Qualitative Studies
(2018-06)
Background: Reframing means changing the way that a person thinks or feels
about a weight loss attempt or weight loss maintenance to enhance its experience
or facilitate its success. Although participants have described ...
Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange).
(2019-08)
Introduction Many patients with psychosis experience everyday social situations as anxiety-provoking. The fears can arise, for example, from paranoia, hallucinations, social anxiety or negative-self beliefs. The fears lead ...
The comments of voices on the appearance of patients with psychosis: ‘the voices tell me that I am ugly’
(2019-09)
Background:There are high rates of obesity and low self-esteem in patients with psychosis. The occurrence of negative voice content directly about appearance is therefore plausible. Derogatory comments about appearance are ...