Browsing Conditions, Lifestyle Factors & Interventions by Author "De Giorgi, Riccardo"
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Antidepressants plus benzodiazepines in major depressive disorder: a clinical dilemma with no recent answers from research
De Giorgi, Riccardo; De Cates, Angharad N (2020-10)Comorbid anxiety symptoms are common in depression, and adding benzodiazepines to antidepressant treatment may seem a rational clinical solution. Benzodiazepines also have potential to reduce the initial anxiety that may ... -
Ketamine for suicidal ideation: New trial challenges current thinking about ketamine
De Giorgi, Riccardo (2022-02)Will ketamine be given to eligible patients with suicidal ideation any time soon? This is hard to say, given the plausible concern that the widespread use of ketamine might trigger a new opioid style crisis.10 Whether ... -
Prevalence of Non-Affective Psychoses in Individuals with Autism Spectrum Disorders: A Systematic Review
De Crescenzo, Franco; De Giorgi, Riccardo (2019-08)Autism spectrum disorders (ASD) and non-affective psychoses such as schizophrenia are commonly acknowledged as discrete entities. Previous research has revealed evidence of high comorbidity between these conditions, but ... -
Psychosocial interventions in stimulant use disorders: a focus on women
De Giorgi, Riccardo; De Crescenzo, Franco (2017-07)Purpose of review: Stimulant use disorders are significant contributors to the global burden of disease, with a growing impact on women. Psychosocial interventions are the gold standard for treating this condition, but ... -
Psychosocial interventions in stimulant use disorders: a systematic review and qualitative synthesis of randomized controlled trials
De Giorgi, Riccardo; Economou, Alexis; De Crescenzo, Franco (2018-09)Stimulant use disorders are highly prevalent with a large burden of disease. Most clinical guidelines recommend psychosocial interventions, but there are no clear hierarchies or indications. Moreover, these interventions ... -
Rischio di mortalità con i farmaci antipsicotici nella popolazione psichiatrica anziana? Una revisione sistematica della letteratura
De Giorgi, Riccardo; Cipriani, Andrea (2016)Scopo dello studio: In Italia, gli anziani raggiungono quasi un quarto della popolazione generale. In questo sottogruppo, gli antipsicotici sono ampiamente prescritti: nonostante siano autorizzati esclusivamente per ... -
Statins for major depressive disorder: A systematic review and meta-analysis of randomized controlled trials
De Giorgi, Riccardo; De Crescenzo, Franco; Cowen, Philip J; Harmer, Catherine J (2021-03)The burden of depressive disorder is large and new treatment approaches are required. Repurposing widely available drugs such as statins may be a time- and cost-effective solution. Statins have anti-inflammatory and ... -
Statins in depression: a repurposed medical treatment can provide novel insights in mental health
De Giorgi, Riccardo; Cowen, Philip J; Harmer, Catherine J (2022-08)Depression has a large burden, but the development of new drugs for its treatment has proved difficult. Progresses in neuroscience have highlighted several physiopathological pathways, notably inflammatory and metabolic ... -
The tail wagging the dog: the diagnostic accuracy of first rank symptoms COMMENTARY ON… COCHRANE CORNER
Townsend, Leigh; De Giorgi, Riccardo (2019-10)Outcomes for people with schizophrenia are improved by expedient diagnosis and specific treatment. ICD-11 and DSM-5 have reduced the importance of Schneider's first rank symptoms (FRS) in the diagnosis of schizophrenia; ... -
Treatment of Inappropriate Sexual Behavior in Dementia
De Giorgi, Riccardo; Series, Hugh (2016-08)Inappropriate sexual behavior (ISB) is a relatively common and potentially disruptive form of behavior in people with dementia. It can cause considerable distress and put placements and people at risk. Yet it is poorly ... -
Vortioxetine for depression: the evidence for its current use in the UK: COMMENTARY ON… COCHRANE CORNER
De Giorgi, Riccardo (2018-12-17)The pharmacological treatment of depression is often hampered by side-effects and unsatisfactory response to treatment. Vortioxetine is one of the newest antidepressants on the market, purportedly with a different mechanism ...