Browsing by Author "Saunders, Kate E.A."
Now showing items 1-20 of 26
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Actigraphic patterns, impulsivity and moodinstability in bipolar disorder, borderlinepersonality disorder and healthy controls.
(2020-01)Objectives:To differentiate the relation between the structure and timing of rest-activity patterns and symptoms of impulsivity and mood instability in bipolar disorder (BD), borderline personality disorder(BPD) and healthy ... -
Behavioural sleep and circadian rhythm interventions in bipolar disorder: a systematic review of randomised controlled trials
(2021-07)Sleep and circadian rhythm disruptions are prominent symptoms of bipolar disorder (BD) and potential targets for adjunctive behavioural intervention. The aim of this systematic review was to appraise evidence from ... -
Characterizing Affective Variability in Bipolar Disorder and Borderline Personality Disorder, and the Effects of Lithium, Using a Generative Model of Affect
(2022-02)The affective variability of Bipolar Disorder (BD) is thought to qualitatively differ from that of Borderline Personality Disorder (BPD), with changes in affect persisting for longer in BD. However, quantitative studies ... -
Cognitive Impairment in Patients with Bipolar Disorder: Impact of Pharmacological Treatment
(2019-12)Bipolar disorder is an illness characterised by periods of elated and depressed mood. These mood episodes are associated with changes in cognitive function and there is evidence to suggest that cognitive dysfunction persists ... -
Considerations in the assessment of capacity
(2020-10)The right of autonomous patients to make decisions about their care is core to medical practice. However, we are frequently faced with situations where a patient is unable to make those decisions because of their medical ... -
Deriving information from missing data: implications for mood prediction
(2020-06)The availability of mobile technologies has enabled the efficient collection prospective longitudinal, ecologically valid self-reported mood data from psychiatric patients. These data streams have potential for improving ... -
Effect of lithium on circadian rhythm in bipolar disorder: A systematic review and meta-analysis
(2021-03)Circadian rhythm disruption is commonly reported in patients with bipolar disorder. Lithium has been suggested to have effects on the circadian clock, the biological basis of the circadian rhythm. The objective of the ... -
Efficacy of digital cognitive behavioral therapy for moderate to severe symptoms of generalized anxiety disorder: A randomized controlled trial
(2020-07)Cognitive behavioral therapy (CBT) is an efficacious intervention for generalized anxiety disorder (GAD). Digital CBT may provide a scalable means of delivering CBT at a population level. We investigated the efficacy of a ... -
The Emerging Circadian Phenotype of Borderline Personality Disorder: Mechanisms, Opportunities and Future Directions
(2021-04)Purpose of Review We review the recent evidence suggesting that circadian rhythm disturbance is a common unaddressed feature of borderline personality disorder (BPD); amelioration of which may confer substantial clinical ... -
Experiences of remote mood and activity monitoring in bipolar disorder: a qualitative study
(2017-01)Mobile technology enables high frequency mood monitoring and automated passive collection of date(e.g.actigraphy) from patients more efficiently and less intrusively than has previously been possible. Such techniques are ... -
Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
(2022-11)The availability of mobile technologies has enabled the efficient collection of prospective longitudinal, ecologically valid self-reported clinical questionnaires from people with psychiatric diagnoses. These data streams ... -
Insomnia as a mediating therapeutic target for depressive symptoms: A sub-analysis of participant data from two large randomized controlled trials of a digital sleep intervention
(2020-06)Insomnia predicts the onset of depression, commonly co-presents with depression and often persists following depression remission. However, these conditions can be challenging to treat concurrently using depression-specific ... -
Learning to Detect Bipolar Disorder and Borderline Personality Disorder with Language and Speech in Non-Clinical Interviews
(2020-08)Bipolar disorder (BD) and borderline personality disorder (BPD) are both chronic psychiatric disorders. However, their overlapping symptoms and common comorbidity make it challenging for the clinicians to distinguish ... -
Mental health prior to and during the COVID-19 pandemic in individuals with bipolar disorder: Insights from prospective longitudinal data
(2022-03)Many studies have examined the impact of COVID-19 on the mental health of the public, but few have focused on individuals with existing severe mental illness with longitudinal data before and during the pandemic. Aims: To ... -
Modelling paralinguistic properties in conversational speech to detect bipolar disorder and borderline personality disorder
(2021-02)Bipolar disorder (BD) and borderline personality disorder (BPD) are two chronic mental health conditions that clinicians find challenging to distinguish based on clinical interviews, due to their overlapping symptoms. In ... -
Mood Homeostasis, Low Mood, and History of Depression in 2 Large Population Samples
(2020-04)Importance Existing therapeutic options are insufficient to tackle the disease burden of depression, and new treatments are sorely needed. Defining new psychotherapeutic targets is challenging given the paucity of coherent ... -
An Overview of Sleep and Circadian Rhythms in Bipolar Disorder
(2022-03)Since the conception of bipolar disorder (BD) as a psychiatric condition, sleep and circadian rhythm disruptions have been cardinal symptoms of the disorder. Current nosologies recognise this and such disruptions form part ... -
The psychiatry virtual-on-call experience: Can it improve confidence of foundation and GP trainees with out-of-hours work in psychiatry?
(2021-06)Out-of-hours (‘on-call’) work can be perceived by junior doctors to be a daunting experience, associated with feeling unprepared and less supported. Simulated on-call programmes have been used to great effect in medicine ... -
Psychosocial markers of age at onset in bipolar disorder: a machine learning approach
(2022-07)Bipolar disorder is a chronic and severe mental health disorder. Early stratification of individuals into subgroups based on age at onset (AAO) has the potential to inform diagnosis and early intervention. Yet, the ... -
A service evaluation of short-term mentalisation based treatment for personality disorder
(2021-08)Background People with personality disorder experience long waiting times for access to psychological treatments, resulting from a limited availability of long-term psychotherapies and a paucity of evidence-based brief ...
