Browsing by Author "Lambe, Sinead"
Now showing items 1-17 of 17
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Agoraphobic avoidance in patients with psychosis: Severity and response to automated VR therapy in a secondary analysis of a randomised controlled clinical trial
Freeman, Daniel; Waite, Felicity; Lambe, Sinead (2022-11)Background: The social withdrawal of many patients with psychosis can be conceptualised as agoraphobic avoidance due to a range of long-standing fears. We hypothesised that greater severity of agoraphobic avoidance is ... -
Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange).
Freeman, Daniel; Lambe, Sinead; Rovira, Aitor; Goodsell, Andrew; Rosebrock, Laina; Geddes, John R; Clark, David M; Waite, Felicity (2019-08)Introduction Many patients with psychosis experience everyday social situations as anxiety-provoking. The fears can arise, for example, from paranoia, hallucinations, social anxiety or negative-self beliefs. The fears lead ... -
Automated virtual reality cognitive therapy versus virtual reality mental relaxation therapy for the treatment of persistent persecutory delusions in patients with psychosis (THRIVE): a parallel-group, single-blind, randomised controlled trial in England with mediation analyses
Freeman, Daniel; Waite, Felicity; Lambe, Sinead; Diamond, Rowan; Rovira, Aitor; Rosebrock, Laina; Clark, David M (2023-09)Persecutory delusions are a major psychiatric problem that often do not respond sufficiently to standard pharmacological or psychological treatments. We developed a new brief automated virtual reality (VR) cognitive treatment ... -
Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses
Freeman, Daniel; Lambe, Sinead; Rosebrock, Laina; Rovira, Aitor; Clark, David M; Waite, Felicity (2022-04)Automated delivery of psychological therapy using immersive technologies such as virtual reality (VR) might greatly increase the availability of effective help for patients. We aimed to evaluate the efficacy of an automated ... -
Catastrophic cognitions about coronavirus: the Oxford psychological investigation of coronavirus questionnaire [TOPIC-Q]
Rosebrock, Laina; Cernis, Emma; Lambe, Sinead; Waite, Felicity; Petit, Ariane; Ehlers, Anke; Clark, David M; Freeman, Daniel (2021-01)Background: Cognitive therapies are developed on the principle that specific cognitive appraisals are key determinants in the development and maintenance of mental health disorders. It is likely that particular appraisals ... -
Coronavirus conspiracy beliefs, mistrust, and compliance with government guidelines in England
Freeman, Daniel; Waite, Felicity; Rosebrock, Laina; Petit, Ariane; Causier, Chiara; East, Anna; Jenner, Lucy; Teale, Ashley-Louise; Carr, Lydia; Mulhall, Sophie; Bold, Emily; Lambe, Sinead (2020-05)Background: An invisible threat has visibly altered the world. Governments and key institutions have had to implement decisive responses to the danger posed by the coronavirus pandemic. Imposed change will increase the ... -
Developing an automated VR cognitive treatment for psychosis: gameChange VR therapy
Lambe, Sinead; Lister, Rachel; Rosebrock, Laina; Rovira, Aitor; Clark, David M; Freeman, Daniel; Waite, Felicity (2020-04)The automated delivery of psychological treatment using virtual reality (VR) has the potential to revolutionise patient access to evidence-based care. VR creates immersive, interactive computer simulations, which elicit ... -
Effects of different types of written vaccination information on COVID-19 vaccine hesitancy in the UK (OCEANS-III): a single-blind, parallel-group, randomised controlled trial
Freeman, Daniel; Waite, Felicity; Rosebrock, Laina; Petit, Ariane; Lambe, Sinead (2021-06)The effectiveness of the COVID-19 vaccination programme depends on mass participation: the greater the number of people vaccinated, the less risk to the population. Concise, persuasive messaging is crucial, particularly ... -
Estimating the Economic Value of Automated Virtual Reality Cognitive Therapy for Treating Agoraphobic Avoidance in Patients With Psychosis: Findings From the gameChange Randomized Controlled Clinical Trial
Freeman, Daniel; Rosebrock, Laina; Lambe, Sinead; Waite, Felicity (2022-11)Background: An automated virtual reality cognitive therapy (gameChange) has demonstrated its effectiveness to treat agoraphobia in patients with psychosis, especially for high or severe anxious avoidance. Its economic ... -
Injection fears and COVID-19 vaccine hesitancy
Freeman, Daniel; Lambe, Sinead; Waite, Felicity; Rosebrock, Laina; Petit, Ariane (2021-06)When vaccination depends on injection, it is plausible that the blood-injection-injury cluster of fears may contribute to hesitancy. Our primary aim was to estimate in the UK adult population the proportion of COVID-19 ... -
“It seems impossible that it’s been made so quickly”: a qualitative investigation of concerns about the speed of COVID-19 vaccine development and how these may be overcome
Brown, Poppy; Waite, Felicity; Lambe, Sinead; Freeman, Daniel (2022-02)The speed of COVID-19 vaccine development has been identified as a central concern contributing to hesitancy in acceptance. We conducted qualitative interviews to gain a greater understanding into these concerns and to ... -
Online Social Endorsement and Covid-19 Vaccine Hesitancy in the United Kingdom
Freeman, Daniel; Lambe, Sinead; Waite, Felicity; Rosebrock, Laina; Jenner, Lucy; Petit, Ariane (2021-04)We explore the implications of online social endorsement for the Covid-19 vaccination program in the United Kingdom. Vaccine hesitancy is a long-standing problem, but it has assumed great urgency due to the pandemic. By ... -
Participatory design to create a VR therapy for psychosis
Lambe, Sinead; Waite, Felicity; Freeman, Daniel (2021-02)This paper describes how participatory design was employed in the design of an automated Virtual Reality (VR) psychological therapy (gameChange), putting people with lived experience of psychosis at the heart of the process. ... -
Psychological framework to understand interpersonal violence by forensic patients with psychosis
Lambe, Sinead; Fazel, Seena; Freeman, Daniel (2023-10)Forensic patients with psychosis often engage in violent behaviour. There has been significant progress in understanding risk factors for violence, but identification of causal mechanisms of violence is limited. Aims To ... -
A safe place to learn: a peer research qualitative investigation of automated virtual reality cognitive therapy (gameChange)
Freeman, Daniel; Rosebrock, Laina; Lambe, Sinead; Waite, Felicity (2023-01)Background: Automated virtual reality (VR) therapy has the potential to substantially increase access to evidence-based psychological treatments. The results of a multicenter randomized controlled trial showed that ... -
A Safe Place to Learn: Peer Research Qualitative Investigation of gameChange Virtual Reality Therapy
Beckley, Ariane; Rosebrock, Laina; Lambe, Sinead; Freeman, Daniel; Waite, Felicity (2023-01)Background: Automated virtual reality (VR) therapy has the potential to substantially increase access to evidence-based psychological treatments. The results of a multicenter randomized controlled trial showed that ... -
Understanding agoraphobic avoidance: the development of the Oxford Cognitions and Defences Questionnaire (O-CDQ)
Rosebrock, Laina; Lambe, Sinead; Mulhall, Sophie; Petit, Ariane; Saidel, Simone; Mitchell, Joanna; Clark, David M; Waite, Felicity; Freeman, Daniel (2022-02)Many patients with mental health disorders become increasingly isolated at home due to anxiety about going outside. A cognitive perspective on this difficulty is that threat cognitions lead to the safety-seeking behavioural ...