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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
(2021-04)
Background
A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the efficacy of the adenoviral vector vaccine, ChAdOx1 ...
Public opinion on global rollout of COVID-19 vaccines
(2021-03)
To the Editor—Vaccination programs for COVID-19 in ‘high-income countries’ (HICs) have benefited from their ability to secure contracts for preferential supply for several vaccines1. For the rest of the world, vaccine ...
Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine
(2021-06)
Early clinical data from studies of the NVX-CoV2373 vaccine (Novavax), a recombinant nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that contains the full-length spike glycoprotein ...
The effect of Long-Term Care (LTC) benefits on healthcare use
(2021-07)
The healthcare systems of most European countries are currently operating under extreme
levels of pressure. Part of this pressure is due to a rising demand for healthcare caused by an
increase in comorbidities and life ...
The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
(2021-08)
Objective
To determine the prevalence of anxiety in general hospital inpatients by conducting a systematic review and meta-analysis of all relevant published studies.
Method
We searched Ovid Medline, Ovid Embase and ...
Learning from nursing students’ experiences and perceptions of their clinical placements in nursing homes: An integrative literature review
(2021-05)
Objectives
This paper aims to investigate pre-registration nursing students' experiences and perceptions of their clinical placements in nursing homes in order to develop recommendations for nurse educators. Evidence ...
Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)
(2021-09)
COVID-19 vaccine supply shortages are causing concerns about compromised immunity in some countries as the interval between the first and second dose becomes longer. Conversely, countries with no supply constraints are ...
Longitudinal trajectory of cardiac magnetic resonance and cardiopulmonary exercise testing findings in moderate to severe COVID-19 and association with symptoms
(2021-10)
Background
Cardiac magnetic resonance (CMR) and cardiopulmonary exercise testing (CPET) have provided important insights into the prevalence of early cardiopulmonary abnormalities in COVID-19 patients. It is currently ...
Factors associated with admission to bed-based care: observational prospective cohort study in a multidisciplinary same day emergency care unit (SDEC)
(2021-01)
Background
The development of ambulatory emergency care services, now called ‘Same Day Emergency Care’ (SDEC) has been advocated to provide sustainable high quality healthcare in an ageing population. However, there are ...