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dc.contributor.authorCipriani, Andrea
dc.identifier.citationJones H, Cipriani A. Barriers and incentives to recruitment in mental health clinical trials. Evidence-Based Mental Health 2019;22:49-50.en
dc.descriptionAvailable in full text with an eligible OpenAthens log in at
dc.description.abstractResearch provides valuable information that improves patients’ outcomes and should inform clinical decision-making.1 There are many research methodologies2 and randomised controlled trials (RCTs) are at the top of the hierarchy, providing the most robust results when efficacy of interventions is concerned.3 RCTs are considered the gold standard because randomisation is the best method we have to remove selection bias between two groups of patients. However, to randomise participants in a trials, there has to be genuine uncertainty in the clinicians over whether a treatment will be beneficial.4 This is called clinical equipoise, which provides the ethical basis for medical research that involves assigning patients to different treatment arms of a clinical trial.5 Notwithstanding all these considerations, it is well recognised that many RCTs struggle to recruit an adequate sample size, with large, collaborative studies often not being able to meet the targets as originally planneden
dc.description.sponsorshipSupported by the NIHRen
dc.subjectRecruitment (Trials)en
dc.subjectRandomised Controlled Trialsen
dc.titleBarriers and incentives to recruitment in mental health clinical trialsen

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