Browsing by Author "De Los Angeles, Alejandro"
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Induced pluripotent stem cells in psychiatry: a critical review
De Los Angeles, Alejandro; Hall, Nicola A; Harrison, Paul J; Tunbridge, Elizabeth (2021-01)A key challenge in psychiatry research is the development of high-fidelity model systems that can be experimentally manipulated to explore and test pathophysiological mechanisms of illness. In this respect, the emerging ... -
Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
Mould, Arne; De Los Angeles, Alejandro; Tunbridge, Elizabeth (2021-04)Alternative splicing (AS) is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or expressed and ...