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Title: | Self-reported depression symptoms in haemodialysis patients: Bi-factor structures of two common measures and their association with clinical factors |
Authors: | Guirguis, Ayman |
Keywords: | Depressive Disorders Haemodialysis |
Issue Date: | Aug-2018 |
Citation: | Chilcot, J., Almond, M. K., Guirguis, A., Friedli, K., Day, C., Davenport, A., Wellstead, D Farrington, K. (2018). Self-reported depression symptoms in haemodialysis patients: Bi-factor structures of two common measures and their association with clinical factors. GENERAL HOSPITAL PSYCHIATRY, 54, 31-36. |
Abstract: | Objective: To validate the factor structure of two common self-report depression tools in a large sample of haemodialysis (HD) patients and to examine their demographic and clinical correlates, including urine output, history of depression and transplantation. Methods: Factor structures of the Beck Depression Inventory (BDI-II) and Patient Health Questionnaire (PHQ-9) were evaluated using confirmatory factor analysis (CFA). Data was utilised from the screening phase (n=709) of a placebo-controlled feasibility randomised control trial (RCT) of sertraline in HD patients with mild to moderate Major Depressive Disorder. Alternative factor models including bi-factor models for the BDI-II and PHQ-9 were evaluated. Coefficient omega and omega-hierarchical were calculated. Results: For both measures, bi-factor measurement models had the overall best fit to the data, with dominant general depression factors. Omega-hierarchical for the general BDI-II and PHQ- 9 factors was 0.94 and 0.88 respectively. Both general factors had high reliability (coefficient omega = 0.97 and 0.94 respectively) and explained over 85% of the explained common variance within their respective models. BDI-II and PHQ-9 general depression factors were negatively associated with age and urine output and positively with a history of depression, antidepressant use within the last 3 months, and a history of failed transplantation. In adjusted regression models, age, urine output and a history of depression remained significant. Conclusions: These data suggest that both the BDI-II and PHQ-9 are sufficiently unidimensional to warrant the use of a total score. Younger age, lower urine output and a history of depression appear consistent correlates of depression severity among HD patients. |
Description: | https://doi.org/10.1016/j.genhosppsych.2018.08.007 |
URI: | https://oxfordhealth-nhs.archive.knowledgearc.net/handle/123456789/349 |
ISSN: | 1873-7714 |
Appears in Collections: | Depressive Disorders |
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