Browsing xMedical Trainees' Publications by Title
Now showing items 4-23 of 27
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Can dietary supplements maintain cognition in mid- to late-life?
(2020-12)Cognitive health, and prevention of its decline to dementia, has risen in prominence with a corresponding exploration of modifiable risk factors to prevent a decline in cognitive health with age. This commentary discusses ... -
Can we prevent seasonal affective disorder (SAD) with melatonergic agents?
(2020-06)Seasonal affective disorder (SAD) is a recurrent form of major depression, particularly occurring in the winter months with a generally spontaneous remission in spring/summer. The predictable nature of this condition ... -
Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine
(2021-04)Objectives To estimate the absolute risk of cerebral venous thrombosis (CVT) and portal vein thrombosis (PVT) in the two weeks following a diagnosis of COVID-19, and to assess the relative risks (RR) compared to influenza ... -
Comorbid Autism Spectrum Disorder and Antisocial Personality Disorder in Forensic Settings
(2021-12)In this editorial, we start from the premise that the commonly held association of ASDs and violence is a misconception. We discuss topics that repeatedly arise in our clinical practice in treating men with an ASD and ASPD ... -
Could health-improving interventions address the growing unemployment crisis?
(2021-02)The COVID-19 pandemic is causing unprecedented rates of unemployment. Poorer mental health is a cause and a consequence of unemployment, and job seekers with poorer mental health remain unemployed for longer. The review ... -
Cyclical Cushing's syndrome and the presentation of a Bipolar Affective state
(2019-12)Affective disorders are relatively frequently observed in patients suffering from endocrine disease. Thus, in Cushing's syndrome, the most common comorbid mental disorder seen is depressive disorder. The rarer cyclical ... -
Depression and anxiety disorders during the COVID-19 pandemic: knowns and unknowns
(2021-10)The COVID-19 pandemic has taken a toll on people's mental health. Yet, the global extent of this impact remains largely unknown. By leveraging the best available data from surveys around the world with measurements of ... -
The effects of intramuscular administration of scopolamine augmentation in moderate to severe major depressive disorder: a randomized, double-blind, placebo-controlled trial
(2020-07)Introduction:Major depressive disorder (MDD) is a common affective disorder. Currently established pharmacotherapies lack rapid clinical response, thereby limiting their ability to bring instant relief to patients. A series ... -
How effective is augmentation with psychotherapy as a next-step option for treatment-resistant depression?
(2020-08)Determining the optimum next-step treatment for the numerous patients with depression who do not adequately respond to an initial trial of medication remains a source of uncertainty in clinical practice. Although a number ... -
Incidence and outcomes of eating disorders during the COVID-19 pandemic
(2021-07)There are concerns that eating disorders have become commoner during the coronavirus disease 2019 (COVID-19) pandemic. Using the electronic health records of 5.2 million people aged under 30, mostly in the USA, we show ... -
Is adjunctive CBT really effective for schizophrenia?
(2019-09)Although antipsychotic medication remains the mainstay of treatment for schizophrenia, medications alone are not always successful. Cognitive– behavioural therapy (CBT) is recommended as an adjunct to pharmacological ... -
Is it time to review NICE guidelines on family therapy for anorexia in young people?
(2020-04)Family therapy is recommended by the National Institute for Health and Care Excellence (NICE) for the management of anorexia nervosa in children and young people, but there is limited evidence to back this recommendation. ... -
Length of hospitalisation for people with severe mental illness: is the longer the better? Commentary on… Cochrane Corner
(2021)The Cochrane review in this month’s Cochrane Corner (Babalola 2014) compares short-stay hospital admission to long-stay/standard admission in patients with severe mental illness for a number of outcomes in a total 2030 ... -
Longitudinal cognitive performance in patients with Bipolar Disorder
(2020-01)Commentary: Neurocognitive impairments are a rather common occurrence in euthymic Bipolar Disorder (BD) patients. Understanding the degree of longitudinal stability of these deficits is vital in the management and treatment ... -
Mood Homeostasis, Low Mood, and History of Depression in 2 Large Population Samples
(2020-04)Importance Existing therapeutic options are insufficient to tackle the disease burden of depression, and new treatments are sorely needed. Defining new psychotherapeutic targets is challenging given the paucity of coherent ... -
My journey into mental healthcare as an international medical graduate (IMG)
(2021-06)Over half of doctors who joined the General Medical Council's (GMC) medical register in the UK in 2020 were from Black, Asian and minority ethnic (BAME) background, and I am one of them. Having experienced clinical settings ... -
Picking up the pieces: psychological therapies for women who experience intimate partner violence
(2021-10)Intimate partner violence (IPV) is highly prevalent worldwide. Women are disproportionately more likely than men to experience IPV towards them at any point in their lifetime. Psychological therapies could be offered to ... -
Psychotropic medication prescribing in people with autism spectrum disorders with and without psychiatric comorbidity
(2021-04)Autism spectrum disorders (ASDs) are a group of lifelong neurodevelopmental disorders characterised by difficulties in social interactions and social communication, and restricted and repetitive behaviours. Relative to the ... -
Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
(2021-01)Background. Neurological and psychiatric sequelae of COVID-19 have been reported, but there are limited data on incidence rates and relative risks. Methods. Using retrospective cohort studies and time-to-event analysis, ... -
Strategies for preventing occupational stress in healthcare workers: past evidence, current problems
(2021)The problem of occupational stress in healthcare workers is hardly new, but effective interventions in this area are lacking despite being sorely needed – especially in the ongoing Covid-19 pandemic. The review ...
