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Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression
(2018)
Risk-taking behaviour is an important component of several psychiatric disorders, including attention-deficit hyperactivity disorder, schizophrenia and bipolar disorder. Previously, two genetic loci have been associated ...
Chronic psychosocial stressors are associated with alterations in salience processing and corticostriatal connectivity.
(2018-12-17)
Psychosocial stressors including childhood adversity, migration, and living in an urban environment, have been
associated with several psychiatric disorders, including psychotic disorders. The neural and psychological ...
Risk factors for interpersonal violence: an umbrella review of meta-analyses
(2018-07)
Background:
Interpersonal violence is a leading cause of morbidity and mortality. The strength and population effect of modifiable risk factors for interpersonal violence, and the quality of the research evidence is not ...
Evaluating the impact of the 5 pillars of parenting programme: A novel parenting intervention for Muslim families
(2018-03-13)
Objective: To evaluate the impact of the 5 Pillars of Parenting Programme, an eight-week parenting intervention group, which incorporates Islamic values and concepts. The evaluation sought to look at outcomes for families ...
Psychiatric disorders, substance use, and executive functioning in older probationers
(2018-11)
Although the number of older people serving community sentences (probation) after conviction for a criminal offence in England and Wales has increased rapidly since about 2006, this population has received little research ...
Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders
(2018-08)
Sleep EEG spindles have been implicated in attention, sensory processing, synaptic plasticity and memory consolidation. In humans, deficits in sleep spindles have been reported in a wide range of neurological and psychiatric ...
The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study
(2018-06)
Whilst the role of the Disrupted-in-Schizophrenia 1 (DISC1) gene in the aetiology of major mental illnesses is debated, the characterisation of its function lends it credibility as a candidate. A key aspect of this functional ...
Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study
(2018-04-23)
The allostatic load index quantifies the cumulative multisystem physiological response to chronic everyday stress, and includes cardiovascular, metabolic and inflammatory measures. Despite its central role in the stress ...
Improving the quality and content of midwives’ discussions with low-risk women about their options for place of birth: Co-production and evaluation of an intervention package
(2018-01)
Objective: Women's planned place of birth is gaining increasing importance in the UK, however evidence suggests
that there is variation in the content of community midwives’ discussions with low risk women about their ...
Task shifting Midwifery Support Workers as the second health worker at a home birth in the UK: A qualitative study
(2018-03)
Objective: Traditionally two midwives attend home births in the UK. This paper explores the implementation of a new home birth care model where births to low risk women are attended by one midwife and one Midwifery Support ...