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Building ‘a compassionate armour’: the journey to develop strength and self‐compassion in a group treatment for complex post‐traumatic stress disorder
(2020-04)
Objectives. Complex post-traumatic stress disorder (PTSD) is associated with severe
difficulties in emotional regulation, interpersonal relationships, and shame. For individuals
with these difficulties, exposure-based ...
Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder
(2020-05)
Bipolar disorder is a chronic neuropsychiatric condition associated with mood instability, where patients present significant sleep and circadian rhythm abnormalities. Currently, the pathophysiology of bipolar disorder ...
Why sleep matters for young people who may get depressed
(2020-04)
Depression and anxiety are negative emotional states familiar to us all through personal experience. Less familiar are severe states of depression, in particular, which can actually shorten the lives of sufferers by over ...
Efficacy and acceptability of pharmacological and non-pharmacological interventions for non-specific chronic low back pain: a protocol for a systematic review and network meta-analysis.
(2020-06)
Background Despite the enormous financial and humanistic burden of chronic low back pain (CLBP), there is little consensus on what constitutes the best treatment options from a multitude of competing interventions. The ...
How women with and without eating disorders perceive their own and others’ bodies: a case-control study
(University of Bristol, 2020-03)
Background: Body dissatisfaction is a key part of the
psychopathology of eating disorders, but there is a lack of consensus
as to whether the dissatisfaction arises from misperception of body
size, and if such misperception ...
Evaluating the Feasibility of Frequent Cognitive Assessment Using the Mezurio Smartphone App: Observational and Interview Study in Adults With Elevated Dementia Risk
(2020-04)
Background: By enabling frequent, sensitive, and economic remote assessment, smartphones will facilitate the detection of early cognitive decline at scale. Previous studies have sustained participant engagement with remote ...
Association Between Neurological Disorders and Death by Suicide in Denmark
(2020-02)
Importance Neurological disorders have been linked to suicide, but the risk across a broad spectrum of neurological disorders remains to be assessed.
Objectives To examine whether people with neurological disorders die ...
Subthalamic nucleus activity dynamics and limb movement prediction in Parkinson’s disease
(2020-02)
Whilst exaggerated bursts of beta frequency band oscillatory synchronization in the subthalamic nucleus have been associated with motor impairment in Parkinson’s disease, a plausible mechanism linking the two phenomena has ...
Stress, inflammation and hippocampal subfields in depression: A 7 Tesla MRI Study
(2020-02)
Experiencing stressful events throughout one’s life, particularly childhood trauma, increases the likelihood of being diagnosed with Major Depressive Disorder (MDD). Raised levels of cortisol, and markers of inflammation ...
Supporting people in mental health crisis in 21st-century Britain
(2020-02)
Recent years have seen a surge in interest in mental healthcare and some reduction
in stigma. Partly as a result of this, alongside a growing population and higher levels
of societal distress, many more people are ...