Procuring and managing diagnostic services, such as laboratory medicine, is generally based on cost and activity. Improving productivity of laboratory services therefore tends to focus on reducing the cost per test. However, ...

Background: Several social and policy developments have led to research partnerships in mental health research, which depart from traditional research models. One form of such partnerships is among research institutions, ...

The innovation pathway by which a newly discovered biomarker is developed into a medical test and used in routine clinical practice comprises a number of different processes split between 2 phases. The first follows on ...

Background The innovation pathway by which a newly discovered biomarker is developed into a medical test and used in routine clinical practice comprises a number of different processes split between 2 phases. The first ...

The field of clinical natural language processing has been advanced significantly since the introduction of deep learning models. The self-supervised representation learning and the transfer learning paradigm became the ...

Relying on large pretrained language models such as Bidirectional Encoder Representations from Transformers (BERT) for encoding and adding a simple prediction layer has led to impressive performance in many clinical natural ...

Background:As people are living longer with higher incidences of long-term health conditions, there is a move towards greater integration of care, including integration of health and social care services. Integrated care ...

Psychiatric genetic research investigates the genetic basis of psychiatric disorders with the aim of more effectively understanding, treating, or, ultimately, preventing such disorders. Given the challenges of recruiting ...

It is important that DTA reviews summarise all the available evidence. Studies in which the necessary information is not fully reported should not necessarily be excluded from pooled analyses. As reported in this article, ...

A common problem in meta-analysis of observational studies arises when the exposure variable is categorical rather than continuous. These data may be referred to as quantile or quintile data (depending on the number of ...