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Now showing items 11-18 of 18
Implementing a digital clinical decision support tool for side effects of antipsychotics: a focus group study
(2019-04-15)
In medicine, algorithms can inform treatment decisions by combining the most up-to-date evidence about side effect profiles of medications, which are comparable in efficacy. Their use provides opportunities for improved ...
ROB-MEN: a tool to assess risk of bias due to missing evidence in network meta-analysis
(2021-11)
Selective outcome reporting and publication bias threaten the validity of systematic reviews and meta-analyses and can affect clinical decision-making. A rigorous method to evaluate the impact of this bias on the results ...
Synthesizing cross-design evidence and cross-format data using network meta-regression
(2022-03)
In network meta-analysis (NMA), we synthesize all relevant evidence about health outcomes with competing treatments. The evidence may come from randomized controlled trials (RCT) or non-randomized studies (NRS) as individual ...
Promoting inclusivity by ensuring that all patients with mental health issues are offered research opportunities in the NHS
(2022-01)
Research-active clinical services have lower mortality rates and produce higher quality care outcomes, however, recruiting participants to clinical research in the National Health System (NHS) remains challenging.1 A recent ...
Producing and using timely comparative evidence on drugs: lessons from clinical trials for covid-19
(2020-10)
Since the early days of the novel coronavirus
outbreak, a record number of studies have been
launched to test several repurposed and new
medicines as potential treatments for covid-19 An
analysis by the news organisation ...
Vitruvian plot: a visualisation tool for multiple outcomes in network meta-analysis
(2022-05)
Objective A network meta-analysis (NMA) usually assesses multiple outcomes across several treatment comparisons. The Vitruvian plot aims to facilitate communication of multiple outcomes from NMAs to patients and ...
Implementation of a Web-Based Resilience Enhancement Training for Nurses: Pilot Randomized Controlled Trial
(2023-02)
Global workforce challenges faced by health care providers are linked to low levels of job satisfaction, recruitment, retention, and well-being, with detrimental impacts on patient care outcomes. Resilience-building programs ...
Estimating and visualising the trade-off between benefits and harms on multiple clinical outcomes in network meta-analysis
(2023-11)
The relative treatment effects estimated from network meta-analysis can be employed to rank treatments from the most preferable to the least preferable option. These treatment hierarchies are typically based on ranking ...