Browsing Nervous System Disorders by Title
Now showing items 13-24 of 24
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Longitudinal Changes in Parkinson’s Disease Symptoms with and Without Rapid Eye Movement Sleep Behavior Disorder: The Oxford Discovery Cohort Study
(2021-08)Background: Parkinson’s disease (PD) comorbid with rapid eye movement sleep behavior disorder (RBD) may show more severe motor and non motor symptoms, suggesting a distinct PD subtype. Objective: The aim of this study was ... -
Mapping brain structural differences and neuroreceptor correlates in Parkinson's disease visual hallucinations: a mega-analysis
(2021-02)Parkinson’s psychosis (PDP) describes a spectrum of symptoms that may arise in Parkinson’s disease (PD) including visual hallucinations (VH). Imaging studies investigating the neural correlates of PDP have been inconsistent ... -
Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients
(2022-08)COVID-19 is associated with increased risks of neurological and psychiatric sequelae in the weeks and months thereafter. How long these risks remain, whether they affect children and adults similarly, and whether SARS-CoV-2 ... -
Outcome domains and measures after lower limb orthopaedic surgery for ambulant children with cerebral palsy: an updated scoping review
(2020-06)Aim: To determine the reported outcome domains and measures used to assess lower limb orthopaedic surgery of ambulant children and young people with cerebral palsy (CP) and map these outcomes to the International Classification ... -
Outcomes of importance to children and young adults with cerebral palsy, their parents and health professionals following lower limb orthopaedic surgery: A qualitative study to inform a Core Outcome Set
(2022-02)Introduction: Although several outcomes are commonly measured to assess the effect of surgery for young people with cerebral palsy (CP), these are selected mainly by health professionals and researchers. Including the ... -
Physical Activity and Fatigue in Multiple Sclerosis: Secondary Outcomes from a Double-blinded Randomized Controlled Trial of Cocoa Flavonoid Drinks
(2021-06)Fatigue is a common and pervasive symptom reducing physical activity in people with multiple sclerosis (pwMS). Exercise may reduce fatigue, although evidence to guide optimal prescription is limited. Specifically, supportive ... -
Predicting motor, cognitive & functional impairment in Parkinson’s
(2019-07)Objective: We recently demonstrated that 998 features derived from a simple 7-minute smartphone test could distinguish between controls, people with Parkinson’s and people with idiopathic Rapid Eye Movement sleep behavior ... -
The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease
(2020-08)Background: Differentiating multiple sclerosis (MS) from vascular risk factor (VRF)-small vessel disease (SVD) can be challenging. Objective and Methods: In order to determine whether or not pontine lesion location ... -
Subthalamic nucleus activity dynamics and limb movement prediction in Parkinson’s disease
(2020-02)Whilst exaggerated bursts of beta frequency band oscillatory synchronization in the subthalamic nucleus have been associated with motor impairment in Parkinson’s disease, a plausible mechanism linking the two phenomena has ... -
Vascular disease and multiple sclerosis: a post-mortem study exploring their relationships
(2020-09)Vascular comorbidities have a deleterious impact on multiple sclerosis clinical outcomes but it is unclear whether this is mediated by an excess of extracranial vascular disease (i.e. atherosclerosis) and/or of cerebral ... -
A web-based life-style, exercise and activity intervention for people with progressive multiple sclerosis: Results of a single-arm feasibility study
(2021-11)Background People with progressive Multiple Sclerosis often struggle to access appropriate and inclusive support for regular physical activity. The Lifestyle, Exercise and Activity Package (LEAP-MS) intervention, is a ... -
A web-based physical activity intervention for People with Progressive Multiple Sclerosis: Application of consensus-based intervention development guidance.
(2021-03)Objectives People with progressive multiple sclerosis (PwPMS) report that they recognise the benefits of activity on their physical and psychological health but need support to achieve their physical activity goals. We ...