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Hippocampal network abnormalities explain amnesia after VGKCC-Ab related autoimmune limbic encephalitis
(2019-05)
Objective Limbic encephalitis associated with antibodies to components of the voltage-gated potassium channel complex (VGKCC-Ab-LE) often leads to hippocampal atrophy and persistent memory impairment. Its long-term impact ...
Cognitive Impairment in Patients with Bipolar Disorder: Impact of Pharmacological Treatment
(2019-12)
Bipolar disorder is an illness characterised by periods of elated and depressed mood. These mood episodes are associated with changes in cognitive function and there is evidence to suggest that cognitive dysfunction persists ...
A critical evaluation of systematic reviews assessing the effect of chronic physical activity on academic achievement, cognition and the brain in children and adolescents: a systematic review
(2020-06)
Background
International and national committees have started to evaluate the evidence for the effects of physical activity on neurocognitive health in childhood and adolescence to inform policy. Despite an increasing ...
Sleep duration over 28 years, cognition, gray matter volume, and white matter microstructure: a prospective cohort study
(2020-01)
Study Objectives
To examine the association between sleep duration trajectories over 28 years and measures of cognition, gray matter volume, and white matter microstructure. We hypothesize that consistently meeting sleep ...
Cognition in Mood Disorders
(2020-01)
Mood disorders are common, complex, and one of the main causes of morbidity worldwide (1).
There has been an increasing recognition that cognitive dysfunction is a central aspect of most
mood disorders, as well as being ...
A single administration of ‘microbial’ D-alanine to healthy volunteers augments reaction to negative emotions: a comparison with D-serine
(2020-03)
Background Activation of the glutamate N-methyl-D-Aspartate receptor (NMDAR) with its co-agonist D-serine has been shown to improve subjective mood in healthy volunteers. D-alanine is another potent NMDAR co-agonist which ...
Prediction of brain age and cognitive age: quantifying brain and cognitive maintenance in aging
(2020-06)
The concept of brain maintenance refers to the preservation of brain integrity in older age, whilecognitive reserverefers to the capacity to maintain cognition in the presence of neurodegeneration or aging-related brain ...
Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
(2020-08)
Importance Prior neuroimaging studies have found that late-life participation in cognitive (eg, reading) and social (eg, visiting friends and family) leisure activities are associated with magnetic resonance imaging (MRI) ...
Precision biomarkers for mood disorders based on brain imaging
(2020-10)
Mood disorders are a global public health problem because of their high prevalence, chronicity, and recurrence throughout the lifespan as well as increased risk of mortality.123 They also impose a heavy economic burden on ...
A common neural network architecture for visual search and working memory
(2020-09)
Visual search and working memory (WM) are tightly linked cognitive processes. Theories of
attentional selection assume that WM plays an important role in top-down guided visual search.
However, computational models of ...