Browsing by Issue Date
Now showing items 41-60 of 1185
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Patient and public involvement in reducing health and care research waste
(2018-01-08)Background: Eighty five per cent of health research expenditure is potentially wasted due to failure to publish research, unclear reporting of research that is published, and the failure of new research studies to ... -
A case series to examine whether people with learning disabilities can learn prerequisite skills for cognitive behavioural therapy
(2018-01-17)Although cognitive behavioural therapy (CBT) is recommended for the treatment of a number of mental disorders among the general population, the ability of individuals with learning disabilities (LD) to understand CBT ... -
Successful recruitment to trials: findings from the SCIMITAR+ Trial
(2018-01-19)Background: Randomised controlled trials (RCT) can struggle to recruit to target on time. This is especially the case with hard to reach populations such as those with severe mental ill health. The SCIMITAR+ trial, a trial ... -
Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis
(2018-01-30)Preclinical models propose that the onset of psychosis is associated with hippocampal hyperactivity, thought to be driven by cortical GABAergic interneuron dysfunction and disinhibition of pyramidal neurons. Recent ... -
A Smartphone App (BlueIce) for Young People Who Self-Harm: Open Phase 1 Pre-Post Trial
(2018-01-30)Background: Recent years have seen a significant increase in the availability of smartphone apps for mental health problems. Despite their proliferation, few apps have been specifically developed for young people, and ... -
Implementation of the back skills training programme
(2018-02)Purpose of study; To evaluate implementation of the Back Skills Training (BeST) programme in clinical practice within the National Health Service (NHS). Background: The BeST programme is a group Cognitive Behavioural ... -
Effectiveness of maintenance therapy of lithium vs other mood stabilizers in monotherapy and in combinations: A systematic review of evidence from observational studies
(2018-02)Objectives: For the first time to present a systematic review of observational studies on the efficiency of lithium monotherapy in comparison with other maintenance mood stabilizers in monotherapy and in combination. Methods: ... -
In-patient treatment in functional and sectorised care: patient satisfaction and length of stay
(2018-02)Background: Debate exists as to whether functional care, in which different psychiatrists are responsible for in- and out-patient care, leads to better in-patient treatment as compared with sectorised care, in which the ... -
Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial
(2018-02-06)Agitation is a common, challenging symptom affecting large numbers of people with dementia and impacting on quality of life (QoL). There is an urgent need for evidence-based, cost-effective psychosocial interventions to ... -
Adding value, reducing research waste, the role of the NHS research and development management community
(2018-02-23)Purpose – Research suggests that 85 per cent of health research is avoidably wasted. The research and development management community has an important role in the research process and can contribute to improving the ... -
Living network meta-analysis compared with pairwise meta-analysis in comparative effectiveness research: empirical study
(2018-02-28)Objective:To examine whether the continuous updating of networks of prospectively planned randomised controlled trials (RCTs) (“living” network meta-analysis) provides strong evidence against the null hypothesis in comparative ... -
Is there a choice to make? A pilot study investigating attitudes towards treatment in an Early Intervention for Psychosis service
(2018-03)Purpose The purpose of this paper is to investigate health care professionals’ (HCPs) and service-users’ (SUs) attitudes towards different treatment options in an Early Intervention for Psychosis (EIP) service as well as ... -
Mechanisms of implementing public health interventions: a pooled causal mediation analysis of randomised trials.
(2018-03)The World Health Organization recommends that nations implement evidence-based nutritional guidelines and policies in settings such as schools and childcare services to improve public health nutrition. Understanding the ... -
A systematic review to explore influences on parental attitudes towards antibiotic prescribing in children
(2018-03)Aims and objectives: To understand the factors influencing parental attitudes towards antibiotic prescribing. Background: Overuse of antibiotics and inappropriate prescribing has resulted in rapid development of antimicrobial ... -
Time to focus more on promoting mental health than treating mental illness
(2018-03)Mental health problems are a major contributor to overall burden of disease worldwide. In UK, it represents up to 23% of the total burden of disease - the largest single cause of disability. To build a healthier, more ... -
Task shifting Midwifery Support Workers as the second health worker at a home birth in the UK: A qualitative study
(2018-03)Objective: Traditionally two midwives attend home births in the UK. This paper explores the implementation of a new home birth care model where births to low risk women are attended by one midwife and one Midwifery Support ... -
GDm‐Health Plus: Development of a remote behavioural lifestyle management system for women with gestational diabetes
(2018-03)Aim: Preventing hyperglycaemia and excessive gestational weight gain through diet and physical activity are central to the management of women with gestational diabetes (GDM), although lifestyle change can be challenging. ... -
Plasma glutathione suggests oxidative stress is equally present in early- and late- onset bipolar disorder
(2018-03)We previously demonstrated oxidative stress in bipolar patients and a relationship between the age of illness onset and total glutathione, a principal antioxi- dant. In this study, we sought to replicate these findings ... -
A Parenting Programme for Muslims
(2018-03)Universal parenting intervention courses often fail to recruit and retain Muslim families. The practice of targeting specific populations in parenting programs is not well established. Parents from minority backgrounds are ... -
Using a modified Delphi methodology to gain consensus on the use of dressings in chronic wounds management
(2018-03-06)Objective:Managing chronic wounds is associated with a burden to patients, caregivers, health services and society and there is a lack of clarity regarding the role of dressings in improving outcomes. This study aimed to ...