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Now showing items 480-499 of 1182
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How effective are physiotherapy interventions in treating people with sciatica? A systematic review and meta-analysis
(2022-12)Purpose: Physiotherapy interventions are prescribed as first-line treatment for people with sciatica; however, their effectiveness remains controversial. The purpose of this systematic review was to establish the short-, ... -
How effective is augmentation with psychotherapy as a next-step option for treatment-resistant depression?
(2020-08)Determining the optimum next-step treatment for the numerous patients with depression who do not adequately respond to an initial trial of medication remains a source of uncertainty in clinical practice. Although a number ... -
How Efficacious Are Antipsychotic Drugs for Schizophrenia? An Interpretation Based on 13 Effect Size Indices
(2021-08)Background The magnitude of the superiority of antipsychotics over placebo is debated. One reason is that the effect-size index which is usually used in meta-analyses is in standard deviation units. Many other indices, ... -
How pharmacist prescribers can help meet the mental health consequences of COVID-19
(2020-11)We suggest that Mental Health Trusts should urgently develop prescribing roles for specialist mental health pharmacists, which are integrated within mental health teams. In these roles, prescribing pharmacists can ... -
How representative are neuroimaging samples? Large-scale evidence for trait anxiety differences between MRI and behaviour-only research participants.
(2020-04)Over the past three decades, MRI has become a key tool to study how cognitive processes are implemented in the human brain. However, the question of whether participants recruited into MRI studies differ from participants ... -
How should we ensure that children are safeguarded in gymnastics?
(2022-03)Gymnastics has had multiple abuse scandals involving the USA, Australia, Europe and the UK [1]. These involve allegations of sexual abuse. In the UK, we are currently awaiting publication of the Whyte Report, an independent ... -
How to build a game for empirical bioethics research: The case of ‘Tracing Tomorrow’
(2021-10)It is becoming increasingly clear that the field of empirical bioethics requires methodological innovations that can keep up with the scale and pace of contemporary research in health and medicine. With that in mind, we ... -
How to manage self-harm in primary care
(2023-01)Mental health specialist nurse Karen Lascelles explains how to approach patients who are self-harming and offer appropriate care and support in line with new NICE guidance. -
How women with and without eating disorders perceive their own and others’ bodies: a case-control study
(University of Bristol, 2020-03)Background: Body dissatisfaction is a key part of the psychopathology of eating disorders, but there is a lack of consensus as to whether the dissatisfaction arises from misperception of body size, and if such misperception ... -
Hummingbird Study: a study protocol for a multicentre exploratory trial to assess the acceptance and performance of a digital medicine system in adults with schizophrenia, schizoaffective disorder or first-episode psychosis
(2019-06)Introduction: In patients with schizophrenia, medication adherence is important for relapse prevention, and effective adherence monitoring is essential for treatment planning. A digital medicine system (DMS) has been ... -
“I'm a man now”: Using NarrativeTherapy to support an adult with Down syndrome transition to a new life
(2023-03)Residential transitions have long been recognised as challenging for people with learning disabilities and can be packed with problem stories. Narrative Therapy practices have the potential to centre the voice of people ... -
IAPT and the internet: The current and future role of therapist-guided internet interventions within routine care settings
(2020-02)Compared to the traditional face-to-face format, therapist-guided internet interventions offer a different approach to supporting clients in learning skills to manage and overcome mental health difficulties. Such interventions ... -
The IBER study: a feasibility randomised controlled trial of Imagery Based Emotion Regulation for the treatment of anxiety in bipolar disorder
(2022-11)Background: Intrusive mental imagery is associated with anxiety and mood instability within bipolar disorder and therefore represents a novel treatment target. Imagery Based Emotion Regulation (IBER) is a brief structured ... -
Identification of Substrate-specific Allosteric Fingerprints in Matrix Metalloprotease-1 on Amyloid-beta Peptide Aggregates and Drug Screening With Single Molecule Insights
(2022-02)Amyloid-beta peptide (Aβ) is the primary component of water-insoluble extracellular plaques, one of the critical hallmarks of Alzheimer's disease (AD). Matrix metalloproteases (MMPs) are broad-spectrum proteases with ... -
Identifying Child Anxiety Through Schools-Identification to Intervention (iCATS-i2i): Protocol for Single-Arm Feasibility Trial
(2021)Anxiety disorders are common among primary-school aged children, but few affected children receive evidence-based treatment. Identifying and supporting children who experience anxiety problems through schools would address ... -
Identifying effective characteristics of behavioral weight management interventions for people with serious mental illness: A systematic review with a qualitative comparative analysis
(2021-10)People with serious mental illness (SMI) have identified barriers to engaging in behavioral weight management interventions (BWMIs). We assessed whether BWMIs that addressed these barriers were more effective. First, we ... -
Identifying individuals at risk of developing psychosis: A systematic review of the literature in primary care services
(2023-01)Psychosis and related disorders are a major public health issue. Early identification and prevention for those at high risk (at-risk-mental-state, ARMS) is important. General practitioners (GPs) are often the first point ... -
Identifying outcomes for depression that matter to patients, informal caregivers, and health-care professionals: qualitative content analysis of a large international online survey
(2020-07)Many clinical trials have assessed treatments for depressive disorders and bipolar depression. However, whether, and which, assessed outcome domains really matter to patients, informal caregivers, and health-care professionals ... -
Identifying psychiatric diagnosis from missing mood data through the use of log-signature features
(2022-11)The availability of mobile technologies has enabled the efficient collection of prospective longitudinal, ecologically valid self-reported clinical questionnaires from people with psychiatric diagnoses. These data streams ... -
Identifying the Top Ten Unanswered Questions in Community Nursing: A James Lind Alliance Priority Setting Partnership in Community Nursing
(2022-11)Community nurses deliver comprehensive nursing care to patients living outside of hospital settings and play a crucial role in meeting individual and public health needs. Research is essential in providing evidence-based ...