Oxford Health Libraries NHS: Recent submissions
Now showing items 941-960 of 1185
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The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function
(2019)Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional ... -
Reducing attendance at trauma clinics by providing first-point-of-contact treatment
(2019-09-02)In 2016, the urgent and ambulatory care service in Oxfordshire formed part of a cross-organisational partnership working group. The group consisted of Oxford Health NHS Foundation Trust community minor injury units (MIUs) ... -
Patient safety regulation in the NHS: mapping the regulatory landscape of healthcare
(2019-07)Objectives The current research project sought to map out the regulatory landscape for patient safety in the English National Health Service (NHS). Method We used a systematic desk-based search using a variety of sources ... -
Is adjunctive CBT really effective for schizophrenia?
(2019-09)Although antipsychotic medication remains the mainstay of treatment for schizophrenia, medications alone are not always successful. Cognitive– behavioural therapy (CBT) is recommended as an adjunct to pharmacological ... -
Moderators and mediators of outcome in treatments for anorexia nervosa and bulimia nervosa in adolescents: A systematic review of randomized controlled trials
(2019-09)Objective:To critically appraise papers reporting on moderators and mediators of recommended psychological treatments for anorexia nervosa (AN) and bulimia nervosa (BN) in adolescents. Method:A systematic search of databases ... -
Characteristics of people with pressure ulcers using one year's routinely collected data in a defined diverse community
(2019-09)Objective:To determine if meaningful patient characteristics pertaining to pressure ulcers (PU) can be derived from routinely collected community health data. Methods: A retrospective cohort analysis of records was carried ... -
A Path Signature Approach for Speech Emotion Recognition
(2019-09)Automatic speech emotion recognition (SER) remains a difficult task within human-computer interaction, despite increasing interest in the research community. One key challenge is how to effectively integrate short-term ... -
Smoking and the risk for bipolar disorder: evidence from a bidirectional Mendelian randomisation study
(2019-09)Background:There is increasing evidence that smoking is a risk factor for severe mental illness, including bipolar disorder. Conversely, patients with bipolar disorder might smoke more (often) as a result of the psychiatric ... -
The weeks before 100 persecutory delusions: the presence of many potential contributory causal factors
(2019-09)Background:The period before the formation of a persecutory delusion may provide causal insights. Patient accounts are invaluable in informing this understanding. Aims:To inform the understanding of delusion formation, ... -
Newly qualified health visitor: Resilience in practice
(2019-09)As a new cohort of health visitors qualify, Bethany Boddy reflects on the importance of resilience and the way individuals, teams and organisations can support staff as they develop their skills as practitioners through ... -
The comments of voices on the appearance of patients with psychosis: ‘the voices tell me that I am ugly’
(2019-09)Background:There are high rates of obesity and low self-esteem in patients with psychosis. The occurrence of negative voice content directly about appearance is therefore plausible. Derogatory comments about appearance are ... -
Collecting self-report research data with people with dementia within care home clinical trials: Benefits, challenges and best practice
(2019-08)One-third of people with dementia live in care home settings and in order to deliver better evidence-based care, robust research including clinical trials is required. Concerns have been raised by researchers about the ... -
Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange).
(2019-08)Introduction Many patients with psychosis experience everyday social situations as anxiety-provoking. The fears can arise, for example, from paranoia, hallucinations, social anxiety or negative-self beliefs. The fears lead ... -
Exercise- and strategy-based physiotherapy-delivered intervention for preventing repeat falls in people with Parkinson's: the PDSAFE RCT.
(2019-07)BACKGROUND: People with Parkinson's disease are twice as likely to experience a fall as a healthy older person, often leading to debilitating effects on confidence, activity levels and quality of life. OBJECTIVE: To ... -
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice
(2019-08)Neuroinflammation and microglial activation are significant processes in Alzheimer’s disease pathology. Recent genome-wide association studies have highlighted multiple immune-related genes in association with Alzheimer’s ... -
Best Methods of Communicating Clinical Trial Data to Improve Understanding of Treatments for Patients with Multiple Sclerosis
(2018-07)Background Patients’ understanding of treatment risks and benefits is a prerequisite for shared decision making. Yet, patients with multiple sclerosis (MS) do not accurately understand treatment information provided in ... -
Paediatric enteral feeding at home: an analysis of patient safety incidents
(2019-06)Aims To describe the nature and causes of patient safety incidents relating to care at home for children with enteral feeding devices. Methods We analysed incident data relating to paediatric nasogastric, gastrostomy ... -
Usability of Health Information Websites Designed for Adolescents: Systematic Review, Neurodevelopmental Model, and Design Brief
(2019-04)Background: Adolescence is a unique developmental period characterized by biological, social, and cognitive changes, as well as an interest in managing one’s own health care. Many adolescents use the internet to seek health ... -
Effects of ketamine treatment on suicidal ideation: a qualitative study of patients’ accounts following treatment for depression in a UK ketamine clinic
(2019-08)Objective It is recognised that ketamine treatment can reduce suicidal ideation (SI) in people with depression, at least in the short term. However, information is lacking on patients’ perspectives on such effects. ... -
Investigating causal mechanisms in randomised controlled trials
(2019-08)Introduction: In some randomised trials, the primary interest is in the mechanisms by which an intervention exerts its effects on health outcomes. That is, clinicians and policy-makers may be interested in how the intervention ...