Oxford Health Libraries NHS: Recent submissions
Now showing items 1141-1160 of 1185
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Patient and public involvement in reducing health and care research waste
(2018-01-08)Background: Eighty five per cent of health research expenditure is potentially wasted due to failure to publish research, unclear reporting of research that is published, and the failure of new research studies to ... -
Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis
(2018-01-30)Preclinical models propose that the onset of psychosis is associated with hippocampal hyperactivity, thought to be driven by cortical GABAergic interneuron dysfunction and disinhibition of pyramidal neurons. Recent ... -
Effectiveness of maintenance therapy of lithium vs other mood stabilizers in monotherapy and in combinations: A systematic review of evidence from observational studies
(2018-02)Objectives: For the first time to present a systematic review of observational studies on the efficiency of lithium monotherapy in comparison with other maintenance mood stabilizers in monotherapy and in combination. Methods: ... -
A Smartphone App (BlueIce) for Young People Who Self-Harm: Open Phase 1 Pre-Post Trial
(2018-01-30)Background: Recent years have seen a significant increase in the availability of smartphone apps for mental health problems. Despite their proliferation, few apps have been specifically developed for young people, and ... -
A case series to examine whether people with learning disabilities can learn prerequisite skills for cognitive behavioural therapy
(2018-01-17)Although cognitive behavioural therapy (CBT) is recommended for the treatment of a number of mental disorders among the general population, the ability of individuals with learning disabilities (LD) to understand CBT ... -
Successful recruitment to trials: findings from the SCIMITAR+ Trial
(2018-01-19)Background: Randomised controlled trials (RCT) can struggle to recruit to target on time. This is especially the case with hard to reach populations such as those with severe mental ill health. The SCIMITAR+ trial, a trial ... -
The effectiveness of the Older prisoner Health and Social Care Assessment and Plan (OHSCAP): a randomised controlled trial
(2017-12)Older prisoners (aged ≥ 50 years) are the fastest growing subgroup in English prisons, and have complex health and social care needs. In a previous study, prisoners and prison and health-care staff worked together to ... -
Elevated homocysteine and N-methyl-D-aspartate-receptor antibodies as a cause of behavioural and cognitive decline in 22q11.2 deletion syndrome
(2017-12)A 19-year-old male with 22q11.2 deletion syndrome presented with a 4-year history of cognitive decline and symptoms suggestive of atypical psychosis. Potential for elevated homocysteine and NMDA-receptor antibodies in the ... -
Discharge pathways and relapse following treatment from early intervention in psychosis services
(2018-04)Early intervention in psychosis (EIP) services are the dominant service model in the treatment of first-episode psychosis. They are a time-limited intervention and little is known about discharge destinations and outcomes ... -
Is Bed Rest Helpful as an Intervention in the Management of Severe Anorexia Nervosa in Hospitals?
(2018-08)Background: Bed rest has been part of treatment of severe anorexia nervosa in hospitals both in the UK and internationally. It is commonly used on medical and paediatric wards and both the adult and Junior MARSIPAN [1] ... -
Helping young people who self-harm
(2017-02)Key learning points: For many young people, the function of self-harm is to escape an unbearable emotional state; relief and negative feelings experienced following self-harm can result in a cycle of self-harming behaviour; ... -
Understanding and working with suicide risk
(2015-07)Key learning points: Understanding risk factors associated with suicide; Considering a framework for understanding suicide; How to assess and manage suicide risk -
Childhood Maltreatment and Violent Outcomes: A Systematic Review and Meta-Analysis of Prospective Studies
(2018-08)The risk of violence following childhood maltreatment is uncertain. This meta-analytic review identified prospective studies that have examined this association. We systematically searched three electronic databases ... -
Predicting treatment response in depression: the role of anterior cingulate cortex
(2018)Background: Identification of biomarkers predicting therapeutic outcome to antidepressant treatment is one of the most important tasks in current research because it may transform the lengthy process of finding the right ... -
A systematic review of co-responder models of police mental health ‘street’ triage
(2018-08)Background: Police mental health street triage is an increasingly common intervention when dealing with police incidents in which there is a suspected mental health component. We conducted a systematic review of street ... -
Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders
(2018-08)Sleep EEG spindles have been implicated in attention, sensory processing, synaptic plasticity and memory consolidation. In humans, deficits in sleep spindles have been reported in a wide range of neurological and psychiatric ... -
‘Coaching and Peer Assisted Learning’ (C‐PAL) ‐The mental health nursing student experience: A qualitative evaluation
(2018)Introduction: This paper presents findings from a study that evaluated mental health nursing students’ experience of a team mentoring model called Coaching and Peer Assisted Learning (C‐PAL). At present there are no ... -
The Experience of Sleep Problems and Their Treatment in Young People at Ultra-High Risk of Psychosis: A Thematic Analysis
(2018-08)We view sleep disruption as a contributory causal factor in the development of psychotic experiences. Clinical trials indicate that psychological interventions targeting insomnia result in improvements in both sleep and ... -
Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis
(2018-08)The benefits and safety of medications for attention-deficit hyperactivity disorder (ADHD) remain controversial, and guidelines are inconsistent on which medications are preferred across different age groups. We aimed to ... -
Improving the effectiveness of psychotherapy in two public hospitals in Nairobi
(2017-08)This paper is the first in a planned series of papers studying the effectiveness of psychotherapy and counselling in Nairobi. It describes a method for checking the effectiveness of psychotherapy and improving service ...