Browsing Interventions by Title
Now showing items 69-88 of 156
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Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis
(2020-03)Background The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies ... -
Frequency of Self-reported Unpleasant Events and Harm in a Mindfulness-Based Program in Two General Population Samples
(2020-12)Objectives Evidence-based mindfulness programs have well-established benefits, but the potential for harmful effects is understudied. We explored the frequency and severity of unpleasant experiences and harm in two ... -
Generating comparative evidence on new drugs and devices before approval
(2020-03)Fewer than half of new drugs have data on their comparative benefits and harms against existing treatment options at the time of regulatory approval in Europe and the USA. Even when active-comparator trials exist, they ... -
Harnessing mobile devices to support the delivery of community-based clinical care: a participatory evaluation
(2019)Background:A large provider of community health services (an NHS Trust in England) deployed Apple iPads to its front-line community-based healthcare clinicians (predominantly nurses) to enable them to increase responsiveness ... -
Hippocampal network abnormalities explain amnesia after VGKCC-Ab related autoimmune limbic encephalitis
(2019-05)Objective Limbic encephalitis associated with antibodies to components of the voltage-gated potassium channel complex (VGKCC-Ab-LE) often leads to hippocampal atrophy and persistent memory impairment. Its long-term impact ... -
How pharmacist prescribers can help meet the mental health consequences of COVID-19
(2020-11)We suggest that Mental Health Trusts should urgently develop prescribing roles for specialist mental health pharmacists, which are integrated within mental health teams. In these roles, prescribing pharmacists can ... -
How should we ensure that children are safeguarded in gymnastics?
(2022-03)Gymnastics has had multiple abuse scandals involving the USA, Australia, Europe and the UK [1]. These involve allegations of sexual abuse. In the UK, we are currently awaiting publication of the Whyte Report, an independent ... -
Hummingbird Study: a study protocol for a multicentre exploratory trial to assess the acceptance and performance of a digital medicine system in adults with schizophrenia, schizoaffective disorder or first-episode psychosis
(2019-06)Introduction: In patients with schizophrenia, medication adherence is important for relapse prevention, and effective adherence monitoring is essential for treatment planning. A digital medicine system (DMS) has been ... -
IAPT and the internet: The current and future role of therapist-guided internet interventions within routine care settings
(2020-02)Compared to the traditional face-to-face format, therapist-guided internet interventions offer a different approach to supporting clients in learning skills to manage and overcome mental health difficulties. Such interventions ... -
Implementing a digital clinical decision support tool for side effects of antipsychotics: a focus group study
(2019-04-15)In medicine, algorithms can inform treatment decisions by combining the most up-to-date evidence about side effect profiles of medications, which are comparable in efficacy. Their use provides opportunities for improved ... -
Implementing a stepped-care psychological pathway for cardiac patients with comorbid anxiety and depression in the UK: a service development project
(2021-03)Background/aims This was a pilot study that was part of a Department of Health and Social Care initiative to improve access to cognitive behavioural therapies for patients with long-term health conditions. The service ... -
The importance of prototype similarity for physical activity: Cross-sectional and longitudinal associations in a large sample of young adolescents
(2022-02)Objectives. Physical activity declines during adolescence. The Theory of Planned Behaviour (TPB) is a useful framework for investigating activity but leaves variance unexplained. We explored the utility of a dual-process ... -
Improving the effectiveness of psychotherapy in two public hospitals in Nairobi
(2017-08)This paper is the first in a planned series of papers studying the effectiveness of psychotherapy and counselling in Nairobi. It describes a method for checking the effectiveness of psychotherapy and improving service ... -
Innovations in Practice: Avatar-based virtual reality in CAMHS talking therapy: two exploratory case studies
(2019-03)Background: Avatar-based virtual reality therapy is an emerging digital technology that can be used to assist the treatment of common mental health problems. This may be particularly appealing to young people who are ... -
Insomnia as a mediating therapeutic target for depressive symptoms: A sub-analysis of participant data from two large randomized controlled trials of a digital sleep intervention
(2020-06)Insomnia predicts the onset of depression, commonly co-presents with depression and often persists following depression remission. However, these conditions can be challenging to treat concurrently using depression-specific ... -
Introducing artificial intelligence in acute psychiatric inpatient care: qualitative study of its use to conduct nursing observations.
(2020-02)Background All patients admitted to an acute inpatient mental health unit must have nursing observations carried out at night either hourly or every 15 minutes, to ascertain that they are safe and breathing. However, while ... -
Introducing the tablet-based Oxford Cognitive Screen-Plus (OCS-Plus) as an assessment tool for subtle cognitive impairments
(2021-04)Here, we present the Oxford Cognitive Screen-Plus, a computerised tablet-based screen designed to briefly assess domain-general cognition and provide more fine-grained measures of memory and executive function. The OCS-Plus ... -
Investigating Different Levels of Bimanual Interaction With a Novel Motor Learning Task: A Behavioural and Transcranial Alternating Current Stimulation Study
(2021-11)In everyday life, we perform countless movements with our hands. Some, such as writing, drawing, or eating with chopsticks, require one hand alone, whereas others require the skilled interaction of both hands. For bimanual ... -
Is placebo response in antidepressant trials rising or not? A reanalysis of datasets to conclude this long-lasting controversy
(2018-01)It had long been believed that placebo response rates in antidepressant trials have been increasing and that they were responsible for rising numbers of so-called failed antidepressant trials. Two recent systematic reviews ... -
Learning to optimize perceptual decisions through suppressive interactions in the human brain
(2019-01)Translating noisy sensory signals to perceptual decisions is critical for successful interactions in complex environments. Learning is known to improve perceptual judgments by filtering external noise and task-irrelevant ...