Molecular and antibody point-of-care tests to support the screening, diagnosis and monitoring of COVID-19

Abstract

Moving diagnostic testing for COVID-19 from laboratory settings to the point of care is potentially transformative in the rate and quantity of testing that could be performed. Eleven diagnostic tests that are potentially suitable for testing for COVID-19 at the point-of-care are described: six molecular tests, and five antibody-based tests. Some devices show high diagnostic accuracy during controlled testing, but performance data from clinical settings, and a clear understanding of the optimal population and role for these tests in the care pathway, are currently lacking.