Conducting Research: Recent submissions
Now showing items 21-40 of 49
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The Kilim plot: A tool for visualizing network meta‐analysis results for multiple outcomes
(2020-06)Network meta‐analysis (NMA) can be used to compare multiple competing treatments for the same disease. In practice, usually a range of outcomes is of interest. As the number of outcomes increases, summarizing results from ... -
Development of A Guideline for Reporting Mediation Analyses (AGReMA)
(2020-02)There are a growing number of studies using mediation analysis to understand the mechanisms of health interventions and exposures. Recent work has shown that the reporting of these studies is heterogenous and incomplete. ... -
A year in statistics—the view from the trenches
(2020-01)Editorial: Last year we launched the EBM Methods Verdicts as part of an attempt to keep on top of developments in statistics that will impact on the way we do research.1 2 We focused on statistical methods and in particular ... -
Ethical implications of poor comparative effectiveness evidence: obligations in industry-research partnerships
(2020-03)Which treatment is best for me? This question is at the centre of the clinical consultation. And yet, too often, the question is not answerable with available evidence on drugs and devices. The two Lancet Series papers on ... -
Investigating assumptions of vulnerability: A case study of the exclusion of psychiatric inpatients as participants in genetic research in low‐ and middle‐income contexts
(2020-01)Psychiatric genetic research investigates the genetic basis of psychiatric disorders with the aim of more effectively understanding, treating, or, ultimately, preventing such disorders. Given the challenges of recruiting ... -
Measuring the impact of participatory research in psychiatry: How the search for epistemic justifications obscures ethical considerations
(2019-12)Both within politics and practice, the field of psychiatry is undergoing a significant transformation, as increasing emphasis is placed on the importance of involving those with lived experience in research. In response ... -
When Deploying Predictive Algorithms, Are Summary Performance Measures Sufficient?
(2020-01)The last decade’s growth in artificial intelligence, machine learning, and statistical methods for high-dimensional data has driven a zeitgeist of prediction (or forecasting) in medicine and psychiatry. Algorithms for ... -
Co-Production: An Ethical Model for Mental Health Research?
(2019-07)Commentary arguing for involving people with a diagnosis of mental health disorders and/or their caregivers as co-researchers in mental health research. -
Consent to discuss participation in research: a pilot study
(2019-09)Background. Equitable access to research studies needs to be increased for all patients. There is debate about which is the best approach to use to discuss participation in research in real-world clinical settings. Objective. ... -
Collecting self-report research data with people with dementia within care home clinical trials: Benefits, challenges and best practice
(2019-08)One-third of people with dementia live in care home settings and in order to deliver better evidence-based care, robust research including clinical trials is required. Concerns have been raised by researchers about the ... -
Investigating causal mechanisms in randomised controlled trials
(2019-08)Introduction: In some randomised trials, the primary interest is in the mechanisms by which an intervention exerts its effects on health outcomes. That is, clinicians and policy-makers may be interested in how the intervention ... -
Can rapid approaches to qualitative analysis deliver timely, valid findings to clinical leaders? A mixed methods study comparing rapid and thematic analysis
(2018-08)Objectives: This study compares rapid and traditional analyses of a UK health service evaluation dataset to explore differences in researcher time and consistency of outputs. Design: Mixed methods study, quantitatively ... -
Qualitative study of barriers to clinical trial retention in adults with recently diagnosed type 1 diabetes
(2018-07)Objectives: Regular physical exercise may preserve β cell function in newly diagnosed adults with type 1 diabetes (T1D). However, clinical trials to test this theory require the recruitment and retention of adults with ... -
R package to identify sudden gains
(PsyArXiv, 2019)Sudden gains are large and stable changes on an outcome variable between consecutive measurements, for example during a psychological intervention with multiple assessments. Researching these occurrences could help understand ... -
Combining Pharmacological and Nonpharmacological Interventions in Network Meta-analysis in Psychiatry
(2019-04)Network meta-analyses (NMAs) assess the comparative associations of 2 or more interventions even if they have not been compared in a randomized clinical trial.1 The validity of NMAs is founded on the assumption of transitivity ... -
Co‐producing research with youth: The NeurOx young people’s advisory group model
(2019-03)Context: The 1989 UN Convention on the Rights of the Child states that children have the right to be heard in all matters affecting them. The Convention inspired a surge in research that investigates young people's ... -
Barriers and incentives to recruitment in mental health clinical trials
(2019-05)Research provides valuable information that improves patients’ outcomes and should inform clinical decision-making.1 There are many research methodologies2 and randomised controlled trials (RCTs) are at the top of the ... -
Mixed effects approach to the analysis of the stepped wedge cluster randomised trial—Investigating the confounding effect of time through simulation
(2018-12)A stepped wedge cluster randomised trial (SWCRT) is a multicentred study which allows an intervention to be rolled out at sites in a random order. Once the intervention is initiated at a site, all participants within that ... -
Applying the triple bottom line of sustainability to healthcare research—a feasibility study
(2019-05)The triple bottom line (TBL) of sustainability is an important emerging conceptual framework which considers the combined economic, environmental and social impacts of an activity. Despite its clear relevance to the ... -
Difficult conversations? Engaging patients in reducing waste in health care
(2016)Purpose – Reducing waste in health care can result in savings that could be used to meet the projected shortfall in NHS funding or to meet the care needs of vulnerable groups. Patients and their families can contribute ...
