Conditions: Recent submissions
Now showing items 321-340 of 698
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Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
(2021-05)Gliomas appear with wide variation in their characteristics both in terms of their appearance and location on brain MR images, which makes robust tumour segmentation highly challenging, and leads to high inter-rater ... -
Onset and recurrence of psychiatric disorders associated with anti-hypertensive drug classes
(2021-05)The major anti-hypertensive (AHT) drug classes have been associated with differential risks of psychiatric disorders. However, existing data are limited largely to depression, and confounding variables have not always been ... -
Changes in daily mental health service use and mortality at the commencement and lifting of COVID-19 'lockdown' policy in 10 UK sites: a regression discontinuity in time design
(2021-05)Objectives: To investigate changes in daily mental health (MH) service use and mortality in response to the introduction and the lifting of the COVID-19 'lockdown' policy in Spring 2020. Design: A regression discontinuity ... -
An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in Chronic Multiple Sclerosis and Neuromyelitis Optica Brain Lesions and Normal Appearing Brain Tissue
(2021-05)Magnetic Resonance Spectroscopy (MRS) allows for the non-invasive quantification of neurochemicals and has the potential to differentiate between the pathologically distinct diseases, multiple sclerosis (MS) and AQP4Ab-positive ... -
Harnessing the nursing contribution to COVID-19 mass vaccination programmes: Addressing hesitancy and promoting confidence
(2021-04)The need for a mass vaccination programme for COVID-19 is considered a pivotal public health strategy to reduce rates of infection, hospitalizations and deaths which have been so much a feature of the past year of the ... -
Clinical prediction tools to identify patients at highest risk of myeloma in primary care: a retrospective open cohort study
(2021-04)Background Patients with myeloma experience substantial delays in their diagnosis, which can adversely affect their prognosis. Aim To generate a clinical prediction rule to identify primary care patients who are at highest ... -
Improving mealtimes for patients and staff within an eating disorder unit: understanding of the problem and first intervention during the pandemic—an initial report
(2021-04)Background Mealtimes occur six times a day on eating disorder (ED) inpatient units and are a mainstay of treatment for EDs. However, these are often distressing and anxiety provoking times for patients and staff. A product ... -
Online Social Endorsement and Covid-19 Vaccine Hesitancy in the United Kingdom
(2021-04)We explore the implications of online social endorsement for the Covid-19 vaccination program in the United Kingdom. Vaccine hesitancy is a long-standing problem, but it has assumed great urgency due to the pandemic. By ... -
Suicidal behavior in individuals accused or convicted of child sex abuse or indecent image offenses: Systematic review of prevalence and risk factors
(2021-04)Objective: An emerging body of research indicates that child sex abuse (CSA) of-fenders are at high risk of suicide when their offenses come to light and that those accused of accessing indecent images of children (IIOC) ... -
Using digital monitoring alongside psychosocial interventions in patients who self-harm
(2021-05)With more than 200,000 presentations to hospital for self-harm each year in England, there is a clear requirement to reduce self-harm and improve well-being in this population. This service evaluation examined the potential ... -
Using the 11-item Version of the RCADS to Identify Anxiety and Depressive Disorders in Adolescents
(2021)The purpose of this study was to identify items from the Revised Children’s Anxiety and Depression Scale – RCADS-C/P that provided a brief, reliable and valid screen for anxiety and/or depressive disorders in adolescents. ... -
Bearing witness to the challenges of breathlessness
(2021-04)The community respiratory nurse specialist (CRNS) supports patients at different stages of lung disease, witnessing the challenge of living with chronic obstructive pulmonary disease (COPD), a progressive illness for which ... -
Statins for major depressive disorder: A systematic review and meta-analysis of randomized controlled trials
(2021-03)The burden of depressive disorder is large and new treatment approaches are required. Repurposing widely available drugs such as statins may be a time- and cost-effective solution. Statins have anti-inflammatory and ... -
Grey matter microstructural differencesin developmental stuttering
(2021-03)Theoretical accounts of developmental stuttering implicate dysfunctional cortico-striatal-thalamo-cortical motor loops through the putamen, but empirical evidence of these proposed differences is currently limited. ... -
‘If he feels better I'll feel better’ relationships with individuals at high-risk of developing psychosis
(2021-03)A large proportion of individuals with an at-risk mental state (ARMS) live at home and are supported by their families. Recommended treatment includes family intervention (FI), and therefore, understanding relationships ... -
Cognitive therapy compared with CBT for social anxiety disorder in adolescents: a feasibility study.
(2021-03)Background Social anxiety disorder (SAD) is common, typically starts in adolescence and has a low natural recovery rate. Existing psychological treatments for adolescent SAD are only moderately effective. It is possible ... -
Ethics of Early Intervention in Alzheimer’s Disease
(2021-03)Alzheimer’s disease (AD) research, treatment, and prevention focus increasingly on developing personalized interventions based on personal genetic, biological, phenotypic data, for early intervention (EI) to limit harm. ... -
Impact of Web-Based Sharing and Viewing of Self-Harm–Related Videos and Photographs on Young People: Systematic Review
(2021-03)Given recent moves to remove or blur self-harm imagery or content on the web, it is important to understand the impact of posting, viewing, and reposting self-harm images on young people. Objective: The aim of this ... -
A web-based physical activity intervention for People with Progressive Multiple Sclerosis: Application of consensus-based intervention development guidance.
(2021-03)Objectives People with progressive multiple sclerosis (PwPMS) report that they recognise the benefits of activity on their physical and psychological health but need support to achieve their physical activity goals. We ... -
Development and Validation of a Novel Dementia Risk Score in the UK Biobank Cohort
(2021-03)INTRODUCTION: Current prognostic models of dementia have had limited success in consistently identifying at-risk individuals. We aimed to develop and validate a novel dementia risk score (DRS) using the UK Biobank cohort. ...