Browsing Conditions by Title
Now showing items 384-403 of 698
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Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study
(2020-04)Background Inflammatory processes have been shown to play a role in dementia. To understand this role, we selected two anti-inflammatory drugs (methotrexate and sulfasalazine) to study their association with dementia ... -
mHealth Interventions for Self-Harm: Scoping Review
(2021-04)Background: Self-harm is a growing issue with increasing prevalence rates; however, individuals who self-harm do not often receive treatment. Mobile health (mHealth) interventions are a possible solution to some of the ... -
Might Informal Carers of Adults With Enduring Suicidality Experience Anticipatory Loss?
(2021-04)Carers of loved ones who repeatedly express suicidal intent and/or engage in suicidal behavior may experience a sense of anticipation of eventual suicide due to the potential of a fatal act of self-harm. An understanding ... -
Mindfulness and acceptance based therapies for psychosis.
(2021-06)This chapter describes two approaches—person-based cognitive therapy (PBCT) and acceptance and commitment therapy (ACT)—that belong to the group of "third-wave" or contextual cognitive-behavioral therapies (CBTs). "Thirdwave" ... -
Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease A Randomized Clinical Trial
(2019-11)IMPORTANCE There are no disease-modifying treatments for Alzheimer disease (AD), the most common cause of dementia. Minocycline is anti-inflammatory, protects against the toxic effects of β-amyloid in vitro and in animal ... -
Misophonia in the UK: norms of the selective sound sensitivity five factor model (S-Five) for misophonia and prevalence of the disorder using a large sample representative of the UK population
(2022-04)What is the reality of the misophonic experience in the general population? This is a study on misophonia in a large sample, representative of the UK general population. The study utilises a multidimensional psychometric ... -
Misophonia in the UK: Prevalence and norms from the S-Five in a UK representative sample
(2023-03)What is the reality of the misophonic experience in the general population? This is a study on misophonia in a large sample, representative of the UK general population. The study utilises a multidimensional psychometric ... -
Modelling paralinguistic properties in conversational speech to detect bipolar disorder and borderline personality disorder
(2021-02)Bipolar disorder (BD) and borderline personality disorder (BPD) are two chronic mental health conditions that clinicians find challenging to distinguish based on clinical interviews, due to their overlapping symptoms. In ... -
Modelling suicide in bipolar disorders: Limitations and opportunities
(2018-07)Commentary on: Malhi GS, Outhred T, Das P et al. Modeling suicide in bipolar disorders. Bipolar Disord. 2018. In their paper in this issue, Malhi et al highlight a key clinical area; whilst suicide rates are increased in ... -
Moderators and mediators of outcome in treatments for anorexia nervosa and bulimia nervosa in adolescents: A systematic review of randomized controlled trials
(2019-09)Objective:To critically appraise papers reporting on moderators and mediators of recommended psychological treatments for anorexia nervosa (AN) and bulimia nervosa (BN) in adolescents. Method:A systematic search of databases ... -
Molecular and antibody point-of-care tests to support the screening, diagnosis and monitoring of COVID-19
(2020-04)Moving diagnostic testing for COVID-19 from laboratory settings to the point of care is potentially transformative in the rate and quantity of testing that could be performed. Eleven diagnostic tests that are potentially ... -
Mood Homeostasis, Low Mood, and History of Depression in 2 Large Population Samples
(2020-04)Importance Existing therapeutic options are insufficient to tackle the disease burden of depression, and new treatments are sorely needed. Defining new psychotherapeutic targets is challenging given the paucity of coherent ... -
Mortality in children and adolescents who present to hospital following non-fatal self-harm: an observational cohort study based on the Multicentre Study of Self-harm in England
(2020-02)Background Self-harm and suicide in children and adolescents are both growing problems, with self-harm associated with a significant risk of subsequent death, particularly suicide. Long-term follow-up studies are necessary ... -
Mortality in psychotic depression: 18-year follow-up study
(2022-10)Background Evidence on the role of co-occurring psychiatric disorders in mortality associated with psychotic depression is limited. Aims To estimate the risk of cause-specific mortality in psychotic depression compared ... -
Mothers’ accounts of the impact of being in nature on postnatal wellbeing: a focus group study
(2023-06)Background The postnatal period is a vulnerable time for mothers to experience stress and mental health difculties. There is increasing evidence that spending time in nature is benefcial for wellbeing. Nature-based ... -
Mothers’ accounts of the impact of being in nature on postnatal wellbeing: a focus group study
(2023-01)The postnatal period is a vulnerable time for mothers to experience stress and mental health difficulties. There is increasing evidence that spending time in nature is beneficial for wellbeing. Nature-based interventions ... -
Motivational Interviewing-based interventions for reducing substance misuse and increasing treatment engagement, retention, and completion in the homeless populations of high-income countries: An equity-focused systematic review and narrative synthesis
(2021-11)Rising mortality and disease prevalence in the homeless have been largely attributed to addiction disorders. This review aimed to assess whether Motivational Interviewing (MI) is effective in changing substance misuse ... -
Multi-scale neural signatures of major depressive, anxiety, and stress-related disorders
(2021-07)The extent of shared and distinct neural mechanisms underlying major depressive disorder (MDD), anxiety and stress-related disorders is still unclear. We compared the neural signatures of these disorders in 5,405 UK Biobank ... -
Multifactorial interventions for preventing falls in older people living in the community: a systematic review and meta-analysis of 41 trials and almost 20 000 participants
(2019-08)Objective To assess the longer term effects of multifactorial interventions for preventing falls in older people living in the community, and to explore whether prespecific trial-level characteristics are associated with ... -
Multisite randomised controlled trial of trauma-focused cognitive behaviour therapy for psychosis to reduce post-traumatic stress symptoms in people with co-morbid post-traumatic stress disorder and psychosis, compared to treatment as usual: study protocol for the STAR (Study of Trauma And Recovery) trial
(2022-05)People with psychosis have high rates of trauma, with a post-traumatic stress disorder (PTSD) prevalence rate of approximately 15%, which exacerbates psychotic symptoms such as delusions and hallucinations. Pilot studies ...