Musculoskeletal Diseases
Recent Submissions
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Actigraphy-derived physical activity levels and circadian rhythm parameters in patients with psoriatic arthritis: relationship with disease activity, mood, age and BMI
(2023-07)Background: Psoriatic arthritis (PsA) is associated with sleep disturbance, depression and a lifetime risk of obesity and cardiovascular disease. To date, there have been no studies investigating the relationship between ... -
An investigation into the relationship between nutritional status, dietary intake, symptoms and health-related quality of life in children and young people with juvenile idiopathic arthritis: a systematic review and meta-analysis
(2023-01)The association between diet, symptoms and health related quality of life in children and young people with Juvenile idiopathic arthritis (JIA) is not clearly understood. The objectives of this systematic review and ... -
How effective are physiotherapy interventions in treating people with sciatica? A systematic review and meta-analysis
(2022-12)Purpose: Physiotherapy interventions are prescribed as first-line treatment for people with sciatica; however, their effectiveness remains controversial. The purpose of this systematic review was to establish the short-, ... -
Risks, roles and responsibilities: Evaluating falls in inpatient mental healthcare settings for older people
(2022-02)Background Despite the large number of falls in mental health settings, we know little about what contributes to falls. The main aim of the study is to explore how fall risk, prevention and management is understood and ... -
Computer-vision aided functional movement measurement in people with and without axial spondyloarthritis – validation and feasibility study protocol
(2021-11)Back pain is a common form of disability worldwide,and one condition that causes chronic back pain is axial spondyloarthritis (axSpA) which primarily affects spinal joints resulting in pain and joint stiffness. There ... -
COVID-19 vaccine hesitancy in systemic sclerosis
(2021-07)In conclusion, our survey suggests that most patients with SSc have positive feelings towards COVID-19 vaccine, but uncertainties are present in a considerable proportion of cases. These results highlight the crucial ... -
Investigating the Mechanisms of Graded Sensorimotor Precision Training in Adults With Chronic Nonspecific Low Back Pain: Protocol for a Causal Mediation Analysis of the RESOLVE Trial
(2021-07)Chronic low back pain (CLBP) is a global health problem associated with an increasing burden on individuals, health care systems, and society. Common treatments for people with CLBP produce, on average, small short-term ... -
Physiotherapists’ perceptions of how patient adherence and non-adherence to recommended exercise for musculoskeletal conditions affects their practice: a qualitative study
(2021-06)Objectives The aim of this study was to explore physiotherapists’ perceptions of how patients’ adherence and non-adherence to recommended exercise affects their practice. Design A qualitative study with a focus group ... -
Relationship between Cardiopulmonary, Mitochondrial and Autonomic Nervous System Function Improvement after an Individualised Activity Programme upon Chronic Fatigue Syndrome Patients
(2021-04)Background: The therapeutic effects of exercise from structured activity programmes have recently been questioned; as a result, this study examines the impact of an Individualised Activity Program (IAP) on the relationship ... -
The different influence of high levels of physical activity on the incidence of knee OA in overweight and obese men and women-a gender specific analysis
(2019-10)Objective To investigate the influence of physical activity on incidence of knee osteoarthritis (OA) in overweight and obese men and women. Design Data were extracted from the Osteoarthritis Initiative cohort on 1,667 ... -
The Convergent Validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS)
(2020-11)Background: Different scales are being used to measure frailty. This study examined the convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Method: The cross-sectional study ... -
Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patients
(2020-10)The purpose of this study was to assess differences in the physiological profiles of completers vs. non-completers following a structured exercise programme (SEP) and the ability to predict non-completers, which is ... -
A single, clinically relevant dose of the GABAB agonist baclofen impairs visuomotor learning
(2020-10)The GABAB agonist baclofen is taken daily as a treatment for spasticity by millions of stroke, brain injury and multiple sclerosis patients, many of whom are also undergoing motor rehabilitation. However, decreases in GABA ... -
Translating the Strengthening and Stretching for Rheumatoid Arthritis of the Hand Programme from clinical trial to clinical practice: An effectiveness–implementation study
(2020-09)Introduction The Strengthening and Stretching for Rheumatoid Arthritis of the Hand programme is a hand exercise programme for people with rheumatoid arthritis. It was clinically effective when delivered during a clinical ... -
The effects of small-needle-knife therapy on pain and mobility from knee osteoarthritis: a pilot randomized-controlled study
(2020-06)Objective:To investigate the effect of small needle-knife therapy in people with painful knee osteoarthritis. Design:Pilot randomised, controlled trial. Setting:Rehabilitation hospital. Subjects:In-patients with ... -
Efficacy and acceptability of pharmacological and non-pharmacological interventions for non-specific chronic low back pain: a protocol for a systematic review and network meta-analysis.
(2020-06)Background Despite the enormous financial and humanistic burden of chronic low back pain (CLBP), there is little consensus on what constitutes the best treatment options from a multitude of competing interventions. The ... -
Potential benefits of a ketogenic diet to improve response and recovery from physical exertion in people with Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A feasibility study
(2019-11)Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) affects approximately 250,000 people in the UK. The condition varies in severity causing long-term physical and cognitive fatigue which is not ... -
Prevalence and treatment of Chronic FatigueSyndrome/Myalgic Encephalomyelitis and co-morbidsevere health anxiety
(2019-11)Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a debilitatingcondition that affects 0.2---0.4% of the population. Health focussed anxiety is common acrossmedical conditions, and may be relevant in CFS/ME. ... -
Multifactorial interventions for preventing falls in older people living in the community: a systematic review and meta-analysis of 41 trials and almost 20 000 participants
(2019-08)Objective To assess the longer term effects of multifactorial interventions for preventing falls in older people living in the community, and to explore whether prespecific trial-level characteristics are associated with ... -
Development and implementation of the physiotherapy-led exercise interventions for the treatment of rotator cuff disorders for the ‘Getting it Right: Addressing Shoulder Pain’ (GRASP) trial
(2019-07)Objectives: The Getting it Right: Addressing Shoulder Pain (GRASP) trial is a large-scale, multicentre, 2 × 2 factorial randomised controlled trial investigating clinical and cost-effectiveness of a progressive exercise ...