Conditions, Lifestyle Factors & Interventions: Recent submissions
Now showing items 541-560 of 910
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Insomnia as a mediating therapeutic target for depressive symptoms: A sub-analysis of participant data from two large randomized controlled trials of a digital sleep intervention
(2020-06)Insomnia predicts the onset of depression, commonly co-presents with depression and often persists following depression remission. However, these conditions can be challenging to treat concurrently using depression-specific ... -
Dissecting Transient Burst Events
(2020-10)Increasing efforts are being made to understand the role of intermittent, transient, high-power burst events of neural activity. These events have a temporal, spectral, and spatial domain. Here, we argue that considering ... -
The impact of the COVID-19 pandemic on self-harm and suicidal behaviour: a living systematic review [version 1; peer review: 1 approved]
(2020-09)Background: The COVID-19 pandemic has caused morbidity and mortality, as well as, widespread disruption to people’s lives and livelihoods around the world. Given the health and economic threats posed by the pandemic to ... -
Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
(2020-08)Importance Prior neuroimaging studies have found that late-life participation in cognitive (eg, reading) and social (eg, visiting friends and family) leisure activities are associated with magnetic resonance imaging (MRI) ... -
Remotely Close during Covid19 Lockdown – exploring Intensive Interaction via Zoom
(2020-09)With the start of the lockdown in response to the coronavirus pandemic it initially seemed that our work would become nigh on impossible. Working in services that provide health and educational support to people with severe ... -
Health Outcome Prioritization in Alzheimer's Disease: Understanding the Ethical Landscape.
(2020-07)BACKGROUND:Dementia has been described as the greatest global health challenge in the 21st century on account of longevity gains increasing its incidence, escalating health and social care pressures. These pressures highlight ... -
Parenting behaviour and paranoia: a network analysis and results from the National Comorbidity Survey-Adolescents (NCS-A)
(2020-08)Method We examined cross-sectional associations of parenting and paranoia in an epidemiologically representative cohort of 10,148 adolescents (National Comorbidity Survey-Adolescents; NCS-A) and a second dataset of 1286 ... -
Learning to Detect Bipolar Disorder and Borderline Personality Disorder with Language and Speech in Non-Clinical Interviews
(2020-08)Bipolar disorder (BD) and borderline personality disorder (BPD) are both chronic psychiatric disorders. However, their overlapping symptoms and common comorbidity make it challenging for the clinicians to distinguish ... -
‘Van Gogh’ syndrome: a term to approach with caution
(2020-06)If Van Gogh syndrome is indeed synonymous with NSSI, then authors would be advised to keep to the latter term and the clear criteria provided by DSM-V. If the literature continues to suggest that there is a specific ... -
The Systemic Assessment Clinic, a Novel Method for Assessing Patients in General Adult Psychiatry: Presentation and Preliminary Service Evaluation.
(2020-08)The traditional model of psychiatric assessment and diagnosis can be criticised as reductive. We developed an innovative model for psychiatric assessment of adult patients referred to our adult mental health team, the ... -
Environmental changes to reduce self-harm on an adolescent inpatient psychiatric ward: an interrupted time series analysis
(2020-07)Existing interventions to reduce self-harm in adolescents admitted to psychiatric wards are usually focused on individual psychological treatments. However, the immediate ward environment in which treatment takes place is ... -
What we learn about bipolar disorder from large-scaleneuroimaging: Findings and future directions from theENIGMA Bipolar Disorder Working Group
(2020-06)MRI-derived brain measures offer a link between genes, the environment and behav-ior and have been widely studied in bipolar disorder (BD). However, many neuroimag-ing studies of BD have been underpowered, leading to varied ... -
The effectiveness of interventions aimed at improving wellbeing and resilience to stress in first responders: A systematic review
(2020-07)First responders are routinely exposed to traumatic critical incidents, placing them at higher risk for developing stress-related psychopathology and associated health problems than the general population. Interventions ... -
Efficacy of digital cognitive behavioral therapy for moderate to severe symptoms of generalized anxiety disorder: A randomized controlled trial
(2020-07)Cognitive behavioral therapy (CBT) is an efficacious intervention for generalized anxiety disorder (GAD). Digital CBT may provide a scalable means of delivering CBT at a population level. We investigated the efficacy of a ... -
Cost and quality-of-life impacts of community treatment orders (CTOs) for patients with psychosis: economic evaluation of the OCTET trial
(2020-07)Purpose:Current RCT and meta-analyses have not found any effect of community treatment orders (CTOs) on hospital or social outcomes. Assumed positive impacts of CTOs on quality-of-life outcomes and reduced hospital costs ... -
The Impact of COVID-19 on the Cancer Care of Adolescents and Young Adults and Their Well-Being: Results From an Online Survey Conducted in the Early Stages of the Pandemic
(2020-07)The COVID-19 pandemic is rapidly evolving, and we learn new details every day. Even though the disrup-tions in our daily routines and health care systems pose many challenges, therein lie many ... -
Identifying outcomes for depression that matter to patients, informal caregivers, and health-care professionals: qualitative content analysis of a large international online survey
(2020-07)Many clinical trials have assessed treatments for depressive disorders and bipolar depression. However, whether, and which, assessed outcome domains really matter to patients, informal caregivers, and health-care professionals ... -
7 Virtual reality (VR) for the treatment of mental health disorders
(2020-07)Mental health disorders are very common, but far too few people receive the best treatments. Much greater access to the best psychological treatments may be achieved using automated delivery in virtual reality (VR). With ... -
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
(2020-07)Background The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be curtailed by vaccination. We assessed the safety, reactogenicity, and immunogenicity of a viral vectored coronavirus vaccine ... -
Addressing concerns about smoking cessation and mental health: theoretical review and practical guide for healthcare professionals
(2020-07)Smoking rates in people with depression and anxiety are twice as high as in the general population, even though people with depression and anxiety are motivated to stop smoking. Most healthcare professionals are aware that ...