Conditions, Lifestyle Factors & Interventions: Recent submissions
Now showing items 481-500 of 910
-
Replay bursts in humans coincide with activation of the default mode and parietal alpha networks
(2020-12)Replay in humans coincides with activity in specific resting brain networks Clusters of heightened default mode and alpha activity are linked to replay bursts These networks are characterized by highly synchronized ... -
An exploration of ending psychotherapy: The experiences of volunteer counsellors
(2020-12)Background/aims Literature suggests that the ending phase of therapy can be difficult and challenging for counsellors. Despite this, there is limited research in this area and no study has specifically looked at the ... -
Are benzodiazepines effective in treating catatonia?
(2020-12)Establishing an evidence base for the clinical management of catatonia is made difficult by the heterogeneous nature of the condition and the limited understanding of its pathophysiology. Benzodiazepines are a mainstay of ... -
Risk, demand and capacity in adult specialist eating disorder services in the South of England – before and since Covid-19
(2020-12)Aims and Method: This is a longitudinal cohort study describing the demand and capacity for specialist inpatient treatment of patients with severe eating disorders covering a population of 3.5 million. We compared the ... -
Do parent factors predict early weight gain in family therapy for anorexia nervosa? Revisiting variables in a community treatment sample
(2020-12)Objective: It is unclear why some children and adolescents respond well to family therapy for anorexia nervosa (AN) and others do not. Previous exploratory studies have suggested that parent variables may be important ... -
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
(2020-12)More than 190 vaccines are currently in development to prevent infection by the novel severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while neutralizing antibodies against the viral spike protein ... -
Glucocorticoid ultradian rhythmicity differentially regulates mood and resting state networks in the human brain: A randomised controlled clinical trial
(2021-02)Adrenal glucocorticoid secretion into the systematic circulation is characterised by a complex rhythm, composed of the diurnal variation, formed by changes in pulse amplitude of an underlying ultradian rhythm of short ... -
Frequency of Self-reported Unpleasant Events and Harm in a Mindfulness-Based Program in Two General Population Samples
(2020-12)Objectives Evidence-based mindfulness programs have well-established benefits, but the potential for harmful effects is understudied. We explored the frequency and severity of unpleasant experiences and harm in two ... -
The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease
(2020-08)Background: Differentiating multiple sclerosis (MS) from vascular risk factor (VRF)-small vessel disease (SVD) can be challenging. Objective and Methods: In order to determine whether or not pontine lesion location ... -
The different influence of high levels of physical activity on the incidence of knee OA in overweight and obese men and women-a gender specific analysis
(2019-10)Objective To investigate the influence of physical activity on incidence of knee osteoarthritis (OA) in overweight and obese men and women. Design Data were extracted from the Osteoarthritis Initiative cohort on 1,667 ... -
Functional organisation for verb generation in children with developmental language disorder
(2020-12)Developmental language disorder (DLD) is characterised by difficulties in learning one's native language for no apparent reason. These language difficulties occur in 7% of children and are known to limit future academic ... -
When Natural Behavior Engages Working Memory
(2020-12)Working memory (WM) enables temporary storage and manipulation of information,1 supporting tasks that require bridging between perception and subsequent behavior. Its properties, such as its capacity, have been thoroughly ... -
Behavioural Experiments in Cognitive Therapy for Posttraumatic Stress Disorder: Why, When, and How?
(2020-11)Behavioural experiments are an integral component of cognitive therapy (CT) for posttraumatic stress disorder (PTSD), but they can be overlooked due to practical constraints and therapist concerns. Here we describe why ... -
Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA
(2020)Background Adverse mental health consequences of COVID-19, including anxiety and depression, have been widely predicted but not yet accurately measured. There are a range of physical health risk factors for COVID-19, but ... -
Treating sleep problems in young people at ultra-high-risk of psychosis: study protocol for a single-blind parallel group randomised controlled feasibility trial (SleepWell).
(2020-11)Background Effective interventions, targeting key contributory causal factors, are needed to prevent the emergence of severe mental health problems in young people. Insomnia is a common clinical issue that is problematic ... -
369 A systematic review to identify and assess the mental health sequalae amongst women with endometriosis with or without chronic pelvic pain (THE ELEMI PROJECT)
(2020-12)Introduction/Background: Endometriosis is a complex, chronic gynaecological condition impacting approximately 176 million women globally. It is associated with symptoms such as chronic pelvic pain (CPP), dysmenorrhoea, ... -
Accuracy of individual and combined risk-scale items in the prediction of repetition of self-harm: multicentre prospective cohort study
(2020-12)Background Individuals attending emergency departments following self-harm have increased risks of future self-harm. Despite the common use of risk scales in self-harm assessment, there is growing evidence that combinations ... -
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
(2020-12)Background Older adults (aged ≥70 years) are at increased risk of severe disease and death if they develop COVID-19 and are therefore a priority for immunisation should an efficacious vaccine be developed. Immunogenicity ... -
Effects of the COVID-19 pandemic on self-harm
(2020-12)There has been extensive discussion, some of it data-based1 but much of it speculative, on the effect of the COVID-19 pandemic on suicide. Since death by suicide requires thorough investigation by professionals, such as ... -
Coproduction with Autistic Adults: Reflections from the Authentistic Research Collective
(2020-12)This article explores coproduction in relation to autistic people. We reflect on the coproduction process with autistic adults from the Authentistic Research Collective at University College London. We aimed to support the ...