Conditions, Lifestyle Factors & Interventions: Recent submissions
Now showing items 401-420 of 910
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The neural correlates of inhibitory control in 10-month-old infants: a functional nearinfrared spectroscopy study
(2021-04)Inhibitory control, a core executive function, emerges in infancy and develops rapidly across childhood. Methodological limitations have meant that studies investigating the neural correlates underlying inhibitory control ... -
Using the 11-item Version of the RCADS to Identify Anxiety and Depressive Disorders in Adolescents
(2021)The purpose of this study was to identify items from the Revised Children’s Anxiety and Depression Scale – RCADS-C/P that provided a brief, reliable and valid screen for anxiety and/or depressive disorders in adolescents. ... -
Bearing witness to the challenges of breathlessness
(2021-04)The community respiratory nurse specialist (CRNS) supports patients at different stages of lung disease, witnessing the challenge of living with chronic obstructive pulmonary disease (COPD), a progressive illness for which ... -
EMD: Empirical Mode Decomposition and Hilbert-Huang Spectral Analyses in Python
(2021-03)The Empirical Mode Decomposition (EMD) package contains Python (>=3.5) functions for analysis of non-linear and non-stationary oscillatory time series. EMD implements a family of sifting algorithms, instantaneous frequency ... -
Dopaminergic modulation of regional cerebral blood flow: An arterial spin labelling study of genetic and pharmacological manipulation of COMT activity
(2021-07)Dopamine has direct and complex vasoactive effects on cerebral circulation. Catechol-O-methyltransferase (COMT) regulates cortical dopamine, and its activity can be influenced both genetically and pharmacologically. COMT ... -
The effect of a one-year vigorous physical activity intervention on fitness, cognitive performance and mental health in young adolescents: the Fit to Study cluster randomised controlled trial
(2021-03)Background Physical activity (PA) may positively stimulate the brain, cognition and mental health during adolescence, a period of dynamic neurobiological development. High-intensity interval training (HIIT) or vigorous ... -
Development of directed global inhibition, competitive inhibition and behavioural inhibition during the transition between infancy and toddlerhood
(2021-04)Abstract Inhibitory control (IC) is a core executive function integral to self-regulation and cognitive control, yet is itself multi-componential. Directed global inhibition entails stopping an action on demand. Competitive ... -
Statins for major depressive disorder: A systematic review and meta-analysis of randomized controlled trials
(2021-03)The burden of depressive disorder is large and new treatment approaches are required. Repurposing widely available drugs such as statins may be a time- and cost-effective solution. Statins have anti-inflammatory and ... -
Implementing a stepped-care psychological pathway for cardiac patients with comorbid anxiety and depression in the UK: a service development project
(2021-03)Background/aims This was a pilot study that was part of a Department of Health and Social Care initiative to improve access to cognitive behavioural therapies for patients with long-term health conditions. The service ... -
Grey matter microstructural differencesin developmental stuttering
(2021-03)Theoretical accounts of developmental stuttering implicate dysfunctional cortico-striatal-thalamo-cortical motor loops through the putamen, but empirical evidence of these proposed differences is currently limited. ... -
‘If he feels better I'll feel better’ relationships with individuals at high-risk of developing psychosis
(2021-03)A large proportion of individuals with an at-risk mental state (ARMS) live at home and are supported by their families. Recommended treatment includes family intervention (FI), and therefore, understanding relationships ... -
The development and testing of a novel Cognitive Behavioural Therapy (CBT)-based intervention to support medicines-related consultations for healthcare professionals
(2021-04)Introduction The cost to healthcare of wasted medicines has been estimated at around £300million per annum (1). In response to this figure and efforts to increase medicines management performance across pharmacy and patient ... -
Cognitive therapy compared with CBT for social anxiety disorder in adolescents: a feasibility study.
(2021-03)Background Social anxiety disorder (SAD) is common, typically starts in adolescence and has a low natural recovery rate. Existing psychological treatments for adolescent SAD are only moderately effective. It is possible ... -
Output planning at the input stage in visual working memory
(2021-03)Working memory serves as the buffer between past sensations and future behavior, making it vital to understand not only how we encode and retain sensory information in memory but also how we plan for its upcoming use. We ... -
Ethics of Early Intervention in Alzheimer’s Disease
(2021-03)Alzheimer’s disease (AD) research, treatment, and prevention focus increasingly on developing personalized interventions based on personal genetic, biological, phenotypic data, for early intervention (EI) to limit harm. ... -
Impact of Web-Based Sharing and Viewing of Self-Harm–Related Videos and Photographs on Young People: Systematic Review
(2021-03)Given recent moves to remove or blur self-harm imagery or content on the web, it is important to understand the impact of posting, viewing, and reposting self-harm images on young people. Objective: The aim of this ... -
A web-based physical activity intervention for People with Progressive Multiple Sclerosis: Application of consensus-based intervention development guidance.
(2021-03)Objectives People with progressive multiple sclerosis (PwPMS) report that they recognise the benefits of activity on their physical and psychological health but need support to achieve their physical activity goals. We ... -
Development and Validation of a Novel Dementia Risk Score in the UK Biobank Cohort
(2021-03)INTRODUCTION: Current prognostic models of dementia have had limited success in consistently identifying at-risk individuals. We aimed to develop and validate a novel dementia risk score (DRS) using the UK Biobank cohort. ... -
Unmet Rehabilitation Needs after Traumatic Brain Injury across Europe: Results from the CENTER-TBI Study
(2021-03)This study aims to assess rehabilitation needs and provision of rehabilitation services for individuals with moderate-to-severe disability and investigate factors influencing the probability of receiving rehabilitation ... -
Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with polypharmacy, but there is little evidence to inform which drug (or dose) should be withdrawn. This study used data from the ...