Conditions, Lifestyle Factors & Interventions: Recent submissions
Now showing items 361-380 of 910
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A retrospective examination of care pathways in individuals with treatment-resistant depression
(2021-05)Individuals with treatment-resistant depression (TRD) experience a high burden of illness. Current guidelines recommend a stepped care approach for treating depression, but the extent to which best-practice care pathways ... -
Psychologic Treatment of Depression Compared With Pharmacotherapy and Combined Treatment in Primary Care: A Network Meta-Analysis
(2021-05)PURPOSE Most patients with depression are treated by general practitioners, and most of those patients prefer psychotherapy over pharmacotherapy. No network meta-analyses have examined the effects of psychotherapy compared ... -
Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
(2021-04)Alternative splicing (AS) is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or expressed and ... -
Shielding working-memory representations from temporally predictable external interference
(2021-05)Protecting working-memory content from distracting external sensory inputs and intervening tasks is a ubiquitous demand in daily life. Here, we ask whether and how temporal expectations about external events can help ... -
A continuum hypothesis of psychotomimetic rapid antidepressants
(2021-05)Ketamine, classical psychedelics and sleep deprivation are associated with rapid effects on depression. Interestingly, these interventions also have common psychotomimetic actions, mirroring aspects of psychosis such as ... -
A qualitative study of stakeholder views on the use of a digital app for supported self-management in early intervention services for psychosis
(2021-06)Background Digital tools such as Smartphones have the potential to increase access to mental health support including self-management interventions for individuals with psychosis, and ultimately to improve outcomes. ... -
Dual-task walking and automaticity after Stroke: Insights from a secondary analysis and imaging sub-study of a randomised controlled trial
(2021-04)Abstract Objective: To test the extent to which initial walking speed influences dual-task performance after walking intervention, hypothesising that slow walking speed affects automatic gait control, limiting executive ... -
mHealth Interventions for Self-Harm: Scoping Review
(2021-04)Background: Self-harm is a growing issue with increasing prevalence rates; however, individuals who self-harm do not often receive treatment. Mobile health (mHealth) interventions are a possible solution to some of the ... -
Effect of serial awake prone positioning on oxygenation in patients admitted to intensive care with COVID-19
(2021-04)Introduction Awake prone positioning (APP) might benefit patients with COVID-19 by improving oxygenation, but it is unknown whether this improvement can be sustained with serial proning episodes. Methods We conducted ... -
Digital health innovation to support sensitive enquiry about female genital mutilation
(2021-05)Health professionals working in community settings are increasingly using mobile technologies to access information and support clients. A Mary Seacole Leadership Award enabled the production of an app, ‘Let's talk FGM’ ... -
Antimicrobial Peptides SLPI and Beta Defensin-1 in Sputum are Negatively Correlated with FEV1
(2021-05)Background: Chronic obstructive pulmonary disease (COPD) and asthma have heterogeneous inflammation with inhaled corticosteroids (ICS) as a mainstay of treatment. There is increased prevalence of non-typeable Haemophilus ... -
A Phenomenological Exploration of the Voices Reported by Borderline Personality and Schizophrenia Patients
(2021-06)Introduction: Over time, there have been different views regarding the verbal auditory hallucinations (VAHs) reported by borderline personality disorder (BPD) and schizophrenia patients. More recently, their similarity has ... -
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Mental health professionals’ experiences of working with parents with psychosis and their families: a qualitative study
(2021-04)Healthcare service users who are parents with psychosis form part of the caseload of most community mental health teams. Mental health professionals can experience uncertainty about how to work with and ask about the ... -
Negative bias in interpretation and facial expression recognition in late life depression: A case control study.
(2021-04)While cognitive bias in younger adults with depression has been extensively researched, there have been relatively few investigations of the presence of cognitive bias in late life depression (LLD). This exploratory study ... -
Assessing recovery in treatment as usual provided by community child and adolescent mental health services
(2021-04)Despite the importance of routinely assessing the outcomes of everyday practice, few studies have reported outcome metrics for child and adolescent mental health services (CAMHS). Aims Our aim is to investigate reliable ... -
Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine
(2021-04)Objectives To estimate the absolute risk of cerebral venous thrombosis (CVT) and portal vein thrombosis (PVT) in the two weeks following a diagnosis of COVID-19, and to assess the relative risks (RR) compared to influenza ... -
Do environmental risk factors for the development of psychosis distribute differently across dimensionally assessed psychotic experiences?
(2021-04)Psychotic experiences (PE) are associated with poorer functioning, higher distress and the onset of serious mental illness. Environmental exposures (e.g. childhood abuse) are associated with the development of PE. However, ... -
Predicting poor outcomes in children aged 1–12 with respiratory tract infections: A systematic review
(2021-04)Background Demand for NHS services is high and rising. In children respiratory tract infections (RTI) are the most common reason for consultation with primary care. Understanding which features are associated with good ... -
Interventions to reduce self-harm on in-patient wards: systematic review
(2021-04)Background Incidents of self-harm are common on psychiatric wards. There are a wide variety of therapeutic, social and environmental interventions that have shown some promise in reducing self-harm in in-patient settings, ...