Browsing Conditions, Lifestyle Factors & Interventions by Subject "Older People"
Now showing items 1-20 of 23
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Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate
(2021-11)Older adults exposed to enriched environments (EE) maintain relatively higher levels of cognitive function, even in the face of compromised markers of brain health. Response speed (RS) is often used as a simple proxy to ... -
Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study
(2018-04-23)The allostatic load index quantifies the cumulative multisystem physiological response to chronic everyday stress, and includes cardiovascular, metabolic and inflammatory measures. Despite its central role in the stress ... -
Altered network stability in progressive supranuclear palsy
(2021-07)The clinical syndromes of Progressive Supranuclear Palsy (PSP) may be mediated by abnormal temporal dynamics of brain networks, due to the impact of atrophy, synapse loss and neurotransmitter deficits. We tested the ... -
Association of midlife stroke risk with structural brain integrity and memory performance at older ages: a longitudinal cohort study
(2020-03)Cardiovascular health in midlife is an established risk factor for cognitive function later in life. Knowing mechanisms of this associationmay allow preventative steps to be taken to preserve brain health and cognitive ... -
Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
(2020-08)Importance Prior neuroimaging studies have found that late-life participation in cognitive (eg, reading) and social (eg, visiting friends and family) leisure activities are associated with magnetic resonance imaging (MRI) ... -
Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol
(2018-11)Introduction: Neurogenic claudication due to spinal stenosis is common in older adults. The effectiveness of conservative interventions is not known. The aim of the study is to estimate the clinical and cost-effectiveness ... -
Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with polypharmacy, but there is little evidence to inform which drug (or dose) should be withdrawn. This study used data from the ... -
Choking Phobia in an Older Adult: A Telephone-Based CBT Case Study Informed by Gerontology
(2022-06)Fear of choking is a relatively understudied phenomenon in older adults, despite the higher incidence of choking to death in this population and the associated mental health burden. This case report presents the use of a ... -
Components, design, and effectiveness of digital physical rehabilitation interventions for older people: a systematic review.
(2020-06)Background With the rapid advancement in digital technologies, the use of digital health applications is increasing day by day. Although a large number of digital applications have been developed for rehabilitation of ... -
Connections Between Insomnia and Cognitive Aging.
(2019-06)Insomnia is a common sleep disorder among older adults, and a risk factor for poor physical and mental health. However, the relationship between insomnia and cognitive health is not well understood. Here, we review ... -
The Convergent Validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS)
(2020-11)Background: Different scales are being used to measure frailty. This study examined the convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Method: The cross-sectional study ... -
Deprescribing antihypertensives in patients with multimorbidity
(2020-10)Deprescribing preventative medications such as antihypertensives may reduce adverse events in some older adults, leading to improved quality of life. The Optimising Treatment for Mild Systolic Hypertension in the ... -
Effectiveness of gait aid prescription for improving spatiotemporal gait parameters and associated outcomes in community-dwelling older people: a systematic review
(2021-07)Purpose To integrate the evidence of gait aid prescription for improving spatiotemporal gait parameters, balance, safety, adherence to gait aid use, and reducing falls in community-dwelling older people. Methods Seven ... -
The importance of different frailty domains in a population based sample in England
(2020-01)Background The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ... -
Multifactorial interventions for preventing falls in older people living in the community: a systematic review and meta-analysis of 41 trials and almost 20 000 participants
(2019-08)Objective To assess the longer term effects of multifactorial interventions for preventing falls in older people living in the community, and to explore whether prespecific trial-level characteristics are associated with ... -
Negative bias in interpretation and facial expression recognition in late life depression: A case control study.
(2021-04)While cognitive bias in younger adults with depression has been extensively researched, there have been relatively few investigations of the presence of cognitive bias in late life depression (LLD). This exploratory study ... -
Prediction of brain age and cognitive age: quantifying brain and cognitive maintenance in aging
(2020-06)The concept of brain maintenance refers to the preservation of brain integrity in older age, whilecognitive reserverefers to the capacity to maintain cognition in the presence of neurodegeneration or aging-related brain ... -
Right Lateralized Brain Reserve Offsets Age-Related Deficits in Ignoring Distraction
(2020-09)Age-related deterioration of attention decreases the ability to stay focused on the task at hand due to less efficient selection of relevant information and increased distractibility in the face of irrelevant, but salient ... -
Rischio di mortalità con i farmaci antipsicotici nella popolazione psichiatrica anziana? Una revisione sistematica della letteratura
(2016)Scopo dello studio: In Italia, gli anziani raggiungono quasi un quarto della popolazione generale. In questo sottogruppo, gli antipsicotici sono ampiamente prescritti: nonostante siano autorizzati esclusivamente per ... -
Risk Factors for Mobility Decline in Community-Dwelling Older Adults: A Systematic Literature Review
(2021-08)Mobility is essential to maintaining independence for older adults. This systematic review aimed to summarize evidence about self-reported risk factors for self-reported mobility decline; and to provide an overview of ...