Browsing Conditions, Lifestyle Factors & Interventions by Issue Date
Now showing items 41-60 of 910
-
Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis
(2018-04)BACKGROUND Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide in adults. Pharmacological and non-pharmacological treatments are available; however, because of ... -
Self-Harm, Suicidal Behaviours, and Cyberbullying in Children and Young People: Systematic Review
(2018-04)Background: Given the concerns about bullying via electronic communication in children and young people and its possible contribution to self-harm, we have reviewed the evidence for associations between cyberbullying ... -
A systematic review exploring therapist competence, adherence, and therapy outcomes in individual CBT for children and young people
(2018-04)Objective: Whilst the evidence base for cognitive behavioural therapy (CBT) with children and young people is growing, the mechanisms through which these beneficial effects occur are still unclear. This systematic review ... -
Web-based rehabilitation interventions for people with rheumatoid arthritis: A systematic review
(2018-04)Background: Rehabilitation approaches for people with rheumatoid arthritis include joint protection, exercises and self-management strategies. Health interventions delivered via the web have the potential to improve access ... -
Staff perceptions of borderline personality disorder and recovery: A Q‐sort method approach
(2018-04)Objectives:This study was the first to explore how staff that work with people diagnosed with borderline personality disorder (BPD) perceive recovery in this client group. These views are important because of the crucial ... -
Sepsis recognition tools in acute ambulatory care: associations with process of care and clinical outcomes in a service evaluation of an Emergency Multidisciplinary Unit in Oxfordshire
(2018-04)Objective: To assess the performance of currently available sepsis recognition tools in patients referred to a community-based acute ambulatory care unit. Design: Service evaluation of consecutive patients over a 4-month ... -
What proportion of patients at the end of life contact out-of-hours primary care? A data linkage study in Oxfordshire
(2018-04)Objectives: Out-of-hours (OOH) primary care services are a key element of community care at the end of life, yet there have been no previous attempts to describe the scope of this activity. We aimed to establish the ... -
Characteristics of patients expressing an interest in ketamine treatment: results of an online survey
(2018-04)Off-label ketamine treatment has shown acute antidepressant effects that offer hope for patients with therapy-resistant depression. However, its potential for integration into treatment algorithms is controversial, not ... -
Adapted CBT to Stabilize Sleep on Psychiatric Wards: a Transdiagnostic Treatment Approach
(2018-04-04)Background: Almost all patients admitted at acute crisis to a psychiatric ward experience clinically significant symptoms of insomnia. Ward environments pose challenges to both sleep and the delivery of therapy. Despite ... -
Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents
(2018-04-20)Major depressive disorder (MDD) in children and adolescents is a recurrent and disabling condition globally but its pathophysiology remains poorly elucidated and there are limited effective treatments available. We performed ... -
Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study
(2018-04-23)The allostatic load index quantifies the cumulative multisystem physiological response to chronic everyday stress, and includes cardiovascular, metabolic and inflammatory measures. Despite its central role in the stress ... -
Accuracy of risk scales for predicting repeat self-harm and suicide: a multicentre, population-level cohort study using routine clinical data
(2018-04-25)Background: Risk scales are used widely in the management of patients presenting to hospital following self-harm. However, there is evidence that their diagnostic accuracy in predicting repeat self-harm is limited. Their ... -
A Systematic Review and Narrative Synthesis to Explore the Effectiveness of Exercise-Based Interventions in Improving Fatigue, Dyspnea, and Depression in Lung Cancer Survivors.
(2018-05)Lung cancer survival rates are increasing; however, lung cancer survivors' mental and physical well-being can suffer from experiencing symptoms of fatigue, dyspnea, and depression. Exercise can improve these symptoms. ... -
Experiences of Reframing during Self-Directed Weight Loss and Weight Loss Maintenance: Systematic Review of Qualitative Studies
(2018-06)Background: Reframing means changing the way that a person thinks or feels about a weight loss attempt or weight loss maintenance to enhance its experience or facilitate its success. Although participants have described ... -
Antidepressants might work for people with major depression: where do we go from here? (Comment)
(2018-06)The publication of our updated network meta-analysis about antidepressants for the acute treatment of major depression has generated a wide discussion in newspapers, social media, and scientific journals. Based on 522 ... -
3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in service personnel
(2018-06)Comment: This current study describes the therapeutic use of MDMA by committed experts in a specialised setting in a small group of participants, most of whom self-referred for the trial. The unmet need for better PTSD ... -
The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study
(2018-06)Whilst the role of the Disrupted-in-Schizophrenia 1 (DISC1) gene in the aetiology of major mental illnesses is debated, the characterisation of its function lends it credibility as a candidate. A key aspect of this functional ... -
Potential Interventions for Preventing Pesticide Self-Poisoning by Restricting Access Through Vendors in Sri Lanka: A Study of Stakeholders' Views
(2018-06)Background: In South Asia, up to one in five individuals who use pesticides for self-harm purchase them immediately prior to the event. Aims: From reviewing the literature we proposed four interventions: (a) farmer ... -
-
Does the UK medical education provide doctors with sufficient skills and knowledge to manage patients with eating disorders safely?
(2018-06)Background: Eating disorders affect 1%–4% of the population and they are associated with an increased rate of mortality and multimorbidity. Following the avoidable deaths of three people the parliamentary ombudsman called ...