Browsing by Subject "Older People"
Now showing items 1-20 of 30
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Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate
(2021-11)Older adults exposed to enriched environments (EE) maintain relatively higher levels of cognitive function, even in the face of compromised markers of brain health. Response speed (RS) is often used as a simple proxy to ... -
Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study
(2018-04-23)The allostatic load index quantifies the cumulative multisystem physiological response to chronic everyday stress, and includes cardiovascular, metabolic and inflammatory measures. Despite its central role in the stress ... -
Altered network stability in progressive supranuclear palsy
(2021-07)The clinical syndromes of Progressive Supranuclear Palsy (PSP) may be mediated by abnormal temporal dynamics of brain networks, due to the impact of atrophy, synapse loss and neurotransmitter deficits. We tested the ... -
Association of midlife stroke risk with structural brain integrity and memory performance at older ages: a longitudinal cohort study
(2020-03)Cardiovascular health in midlife is an established risk factor for cognitive function later in life. Knowing mechanisms of this associationmay allow preventative steps to be taken to preserve brain health and cognitive ... -
Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
(2020-08)Importance Prior neuroimaging studies have found that late-life participation in cognitive (eg, reading) and social (eg, visiting friends and family) leisure activities are associated with magnetic resonance imaging (MRI) ... -
Autism in Older Adults
(2022-06)Previously, autism had been predominantly labelled as a disorder of childhood, however, evidence now shows that autism is a lifelong condition. This assignment aims to explore autism in older adults by discussing the ... -
Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol
(2018-11)Introduction: Neurogenic claudication due to spinal stenosis is common in older adults. The effectiveness of conservative interventions is not known. The aim of the study is to estimate the clinical and cost-effectiveness ... -
Blood pressure changes following antihypertensive medication reduction, by drug class and dose chosen for withdrawal: Exploratory analysis of data from the OPTiMISE trial
(2021-02)Aims: Deprescribing of antihypertensive drugs is recommended for some older patients with polypharmacy, but there is little evidence to inform which drug (or dose) should be withdrawn. This study used data from the ... -
Choking Phobia in an Older Adult: A Telephone-Based CBT Case Study Informed by Gerontology
(2022-06)Fear of choking is a relatively understudied phenomenon in older adults, despite the higher incidence of choking to death in this population and the associated mental health burden. This case report presents the use of a ... -
Components, design, and effectiveness of digital physical rehabilitation interventions for older people: a systematic review.
(2020-06)Background With the rapid advancement in digital technologies, the use of digital health applications is increasing day by day. Although a large number of digital applications have been developed for rehabilitation of ... -
Connections Between Insomnia and Cognitive Aging.
(2019-06)Insomnia is a common sleep disorder among older adults, and a risk factor for poor physical and mental health. However, the relationship between insomnia and cognitive health is not well understood. Here, we review ... -
The Convergent Validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS)
(2020-11)Background: Different scales are being used to measure frailty. This study examined the convergent validity of the electronic Frailty Index (eFI) with the Clinical Frailty Scale (CFS). Method: The cross-sectional study ... -
Deprescribing antihypertensives in patients with multimorbidity
(2020-10)Deprescribing preventative medications such as antihypertensives may reduce adverse events in some older adults, leading to improved quality of life. The Optimising Treatment for Mild Systolic Hypertension in the ... -
Effectiveness of gait aid prescription for improving spatiotemporal gait parameters and associated outcomes in community-dwelling older people: a systematic review
(2021-07)Purpose To integrate the evidence of gait aid prescription for improving spatiotemporal gait parameters, balance, safety, adherence to gait aid use, and reducing falls in community-dwelling older people. Methods Seven ... -
The effectiveness of the Older prisoner Health and Social Care Assessment and Plan (OHSCAP): a randomised controlled trial
(2017-12)Older prisoners (aged ≥ 50 years) are the fastest growing subgroup in English prisons, and have complex health and social care needs. In a previous study, prisoners and prison and health-care staff worked together to ... -
Experiences of Ambulatory Care for Frail, Older People and Their Carers During Acute Illness: A Qualitative, Ethnographic Study
(2019-05)Increased age is associated with increased emergency department attendance and emergency hospital admissions, but there is evidence that the acute hospital environment is unsuited to older people with frailty.There are ... -
Factors associated with admission to bed-based care: observational prospective cohort study in a multidisciplinary same day emergency care unit (SDEC)
(2021-01)Background The development of ambulatory emergency care services, now called ‘Same Day Emergency Care’ (SDEC) has been advocated to provide sustainable high quality healthcare in an ageing population. However, there are ... -
The importance of different frailty domains in a population based sample in England
(2020-01)Background The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, ... -
Improving the rehabilitation of older people after emergency hospital admission
(2018-05)Purpose: Older adults are at risk of functional decline during emergency hospital admissions. This review aims to understand which exercise-based interventions are effective in improving function for older adults who ... -
Multifactorial interventions for preventing falls in older people living in the community: a systematic review and meta-analysis of 41 trials and almost 20 000 participants
(2019-08)Objective To assess the longer term effects of multifactorial interventions for preventing falls in older people living in the community, and to explore whether prespecific trial-level characteristics are associated with ...